ADORA2B

  • Official Full Name

    adenosine A2b receptor
  • Overview

    This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.
  • Synonyms

    ADORA2B;adenosine A2b receptor;adenosine receptor A2b;ADORA2

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • Chicken
  • Zebrafish
  • Bovine
  • Oryctolagus cuniculus (Rabbit)
  • Mus musculus
  • Dog
  • E.coli
  • Mammalian Cell
  • E.Coli or Yeast
  • Wheat Germ
  • HEK293
  • E. coli
  • In Vitro Cell Free System
  • E.coli expression system
  • His&SUMO
  • His
  • Non
  • N-His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ADORA2B-300H Recombinant Human ADORA2B protein, His-SUMO-tagged E.coli Human His&SUMO Gln260~Leu332
ADORA2B-1372M Recombinant Mouse ADORA2B Protein Mammalian Cell Mouse His
Adora2b-3163R Recombinant Rat Adora2b, His-tagged E.Coli or Yeast Rat His 332
ADORA2B-3164C Recombinant Chicken ADORA2B, His-tagged E.Coli or Yeast Chicken His 340
ADORA2B-3656Z Recombinant Zebrafish ADORA2B Mammalian Cell Zebrafish His
ADORA2B-370H Recombinant Human ADORA2B Protein Wheat Germ Human Non
ADORA2B-534R Recombinant Rat ADORA2B Protein Mammalian Cell Rat His
ADORA2B-6644C Recombinant Chicken ADORA2B Mammalian Cell Chicken His
ADORA2B-9005HCL Recombinant Human ADORA2B 293 Cell Lysate HEK293 Human Non
ABCB8-3533H Recombinant Human ABCB8 protein, His-tagged E. coli Human N-His 403-596 aa
ADORA2B-190R Recombinant Rat ADORA2B Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ADORA2B-190R-B Recombinant Rat ADORA2B Protein Pre-coupled Magnetic Beads HEK293 Rat
ADORA2B-2957H Recombinant Human ADORA2B Full Length Transmembrane protein(Nanodisc) HEK293 Human Non Full L.
ADORA2B-357M Recombinant Mouse ADORA2B Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ADORA2B-357M-B Recombinant Mouse ADORA2B Protein Pre-coupled Magnetic Beads HEK293 Mouse
ADORA2B-972HF Recombinant Full Length Human ADORA2B Protein In Vitro Cell Free System Human Full L. 332 amino acids
RFL-14450RF Recombinant Full Length Rat Adenosine Receptor A2B(Adora2B) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length (1-332)
RFL22198BF Recombinant Full Length Bovine Adenosine Receptor A2B(Adora2B) Protein, His-Tagged E.coli expression system Bovine His Full L. Full Length (1-332)
RFL24773OF Recombinant Full Length Rabbit Adenosine Receptor A2B(Adora2B) Protein, His-Tagged E.coli expression system Oryctolagus cuniculus (Rabbit) His Full L. Full Length (1-332)
RFL26241MF Recombinant Full Length Mouse Adenosine Receptor A2B(Adora2B) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-332)
RFL-32929HF Recombinant Full Length Human Adenosine Receptor A2B(Adora2B) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-332)
RFL-8285GF Recombinant Full Length Chicken Adenosine Receptor A2B(Adora2B) Protein, His-Tagged E.coli expression system Chicken His Full L. Full Length (1-340)
RFL9201CF Recombinant Full Length Dog Adenosine Receptor A2B(Adora2B) Protein, His-Tagged E.coli expression system Dog His Full L. Full Length (1-332)

    Involved Pathway

    ADORA2B involved in several pathways and played different roles in them. We selected most pathways ADORA2B participated on our site, such as Adenosine P1 receptors,Alcoholism,C-MYB transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADORA2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network MYOD1,PIAS3,LECT2,PTCRA,CDKN1B,SKI,YEATS4,CBX4,CSF1R,ADA
    GPCR downstream signaling PLEKHG2,S1PR5B,OPN4,LPAR1,GRP,GPRC6A,RXFP2B,LPAR2B,INSL5,OPN4B
    Adenosine P1 receptors ADORA1,ADORA3,ADORA2A
    Class A/1 (Rhodopsin-like receptors) CGA,ADRB2,LPAR5A,GPR55,SSTR3,ADRA2B,GPR37L1,ANXA1,GPR18,UTS2
    Alcoholism CRH,HIST3H2A,HIST1H2AB,GRIN2A,HIST1H4J,HIST1H2AO,HIST2H4,SHC1,GNG10,CAMK4
    Calcium signaling pathway EDNRBA,PPP3R2,P2RX3,PRKCBA,NOS3,CACNA1C,PLCB1,ADORA2AB,GNAL,EDNRAA
    GPCR ligand binding GPR120,SST,NPS,DRD4,RGR,GPR18,CCL19A.2,CCL27,ADORA2A,OPN4.1
    G alpha (s) signalling events GCGA,PTH2,RLN3,CALCA,VIP,RAMP1,GPBAR1,RAMP3,NPS,ADM2A

    Protein Function

    ADORA2B has several biochemical functions, for example, G-protein coupled adenosine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADORA2B itself. We selected most functions ADORA2B had, and list some proteins which have the same functions with ADORA2B. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled adenosine receptor activity ADORA2AA,ADORA1,ADORA2AB,ADORA3,ADORA2A,P2RY12

    Interacting Protein

    ADORA2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADORA2B here. Most of them are supplied by our site. Hope this information will be useful for your research of ADORA2B.

    TPD52L2;ZNF267

    Resources

    References

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