ACLY
-
Official Full Name
ATP citrate lyase -
Synonyms
ACLY;ATP citrate lyase;ATP-citrate synthase;ACL;ATP citrate synthase;ATPCL;CLATP;citrate cleavage enzyme;ATP-citrate (pro-S-)-lyase
Recombinant Proteins
- Human
- Chicken
- Rat
- Mouse
- E. coli
- Mammalian Cell
- Insect Cells
- E.Coli or Yeast
- Insect cells
- Insect Cell
- E.coli
- HEK293T
- HEK293
- N-His
- His
- GST
- Non
- Myc&DDK
- His&SUMO
Involved Pathway
ACLY involved in several pathways and played different roles in them. We selected most pathways ACLY participated on our site, such as Citrate cycle (TCA cycle),Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACLY were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ITPK1,ATP6V1D,COX8C,XYLT2,BCO1L,GCLC,DOLK,ACSM5,SPTLC3,AZIN2 |
| Citrate cycle (TCA cycle) | MDH1AA,IDH3G,PDHA1B,SUCLG2,IDH3A,ACLYA,PDHB,CS,OGDHL,OGDH |
Protein Function
ACLY has several biochemical functions, for example, ATP binding,ATP citrate synthase activity,cofactor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACLY itself. We selected most functions ACLY had, and list some proteins which have the same functions with ACLY. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | PIP5K1A,TEP1,NAT1,GK5,AACS,UBE2L3A,CDK11A,ABCB5,KIF1B,CKMT1A |
| cofactor binding | TKT,LMO2,C3,HACL1,ME3,DAO,HIF1AN,UROS,WWOX,PHYH |
| protein binding | UNC45A,UBE2L6,FRA10AC1,VBP1,HPN,RPS26,COL23A1,TSC1,DAG1,PAQR5 |
| metal ion binding | CHPT1,F13A1,AARSD1,NAIP7,SOBPA,HINFP,NEK8,PHYH,COLEC12,HSCB |
| ATP citrate synthase activity | ACLYA |
Interacting Protein
ACLY has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACLY here. Most of them are supplied by our site. Hope this information will be useful for your research of ACLY.
BCAR3;TFE3;NME2;VHL;GSK3B;ARF6;CCNA1;IKBKE;TNFRSF10D;PRKAB1;q7cg03_yerpe;hemL2;TFAP2C;q9wmx2-pro_0000037551;15-deoxy-delta(12,14;ere_dna
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References
- Kettenbach, AN; Sano, H; et al. SPECHT - Single-stage phosphopeptide enrichment and stable-isotope chemical tagging: Quantitative phosphoproteomics of insulin action in muscle. JOURNAL OF PROTEOMICS 114:48-60(2015).
- Zhang, JL; Hochwald, SN; et al. The role of FAK in tumor metabolism and therapy. PHARMACOLOGY & THERAPEUTICS 142:154-163(2014).
