ABP1
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Official Full Name
amiloride binding protein 1 (amine oxidase (copper-containing)) -
Overview
This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. -
Synonyms
ABP1;amiloride binding protein 1 (amine oxidase (copper-containing));amiloride-sensitive amine oxidase [copper-containing];AOC1;DAO;ABP;ABP1_HUMAN;Amiloride binding protein 1 (amine oxidase (copper containing));Amiloride binding protein 1;Amiloride binding protein;Amiloride sensitive amine oxidase;Amiloride-binding protein;DAO1;Diamine oxidase;Histaminase;KAO;Kidney amine oxidase;amiloride-binding protein-1;amiloride-sensitive amine oxidase
Recombinant Proteins
- Human
- Rat
- Maize
- E.coli
- Wheat Germ
- E.Coli/Yeast
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ABP1-9255H | Recombinant Human ABP1, GST-tagged | E.coli | Human | GST | 400-751a.a. | |
| ABP1-112H | Recombinant Human ABP1 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ABP1-113H | Recombinant Human ABP1 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
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| ABP1-114H | Recombinant Human ABP1 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
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| ABP1-3409H | Recombinant Human ABP1, His-tagged | E.Coli/Yeast | Human | His | 751 |
|
| Abp1-3410R | Recombinant Rat Abp1, His-tagged | E.Coli/Yeast | Rat | His | 746 |
|
| ABP1-9123HCL | Recombinant Human ABP1 293 Cell Lysate | HEK293 | Human | Non |
|
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| ABP1-1265M | Recombinant Maize ABP1 Protein (39-201 aa), His-tagged | E.coli | Maize | His | 39-201 aa |
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| ABP1-15H | Recombinant Human ABP1 Protein, His-tagged | HEK293 | Human | His | Glu20-Val751 |
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| ABP1-16H | Recombinant Human ABP1 Protein, His-tagged | E.coli | Human | His | Thr400-Val751 |
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| ABP1-3862M | Recombinant Maize ABP1 protein, His-tagged | E.coli | Maize | His | 39-201aa |
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| ABP1-832HF | Recombinant Full Length Human ABP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 751 amino acids |
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| ABP1-834HF | Recombinant Full Length Human ABP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 751 amino acids |
|
Involved Pathway
ABP1 involved in several pathways and played different roles in them. We selected most pathways ABP1 participated on our site, such as Arginine and proline metabolism,Histidine metabolism,Tryptophan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Histidine metabolism | AMDHD1,ASPA,ALDH3A2,ALDH3A1,ALDH9A1B,UROC1,ALDH1B1,ALDH2.2,HNMT,AOC1 |
| Arginine and proline metabolism | ALDH4A1,PRODH,ALDH9A1,GOT2B,DAO.3,CKM,ARG2,AMD1,AZIN2,ARG1 |
| Tryptophan metabolism | AOX3,GCDHA,TPH1B,ACAT2,AOX1,AADAT,KYNU,ALDH9A1A.1,ALDH2.2,TPH1 |
| Metabolic pathways | ALDH9A1A.1,HSD17B2,SPHK1,MECR,RDH8,UPP1,AKR1B7,ITPKB,ATP5G3B,PON2 |
Protein Function
ABP1 has several biochemical functions, for example, calcium ion binding,copper ion binding,diamine oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABP1 itself. We selected most functions ABP1 had, and list some proteins which have the same functions with ABP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein complex binding | ANKRD32,NCKAP1,DLG4,CDKN1A,NCOA1,FLCN,LCA5,GIT1,RPTOR,MYSM1 |
| zinc ion binding | RBBP6,LHX8A,TRIM55B,ADAMTS7,ZDHHC5A,TRIM35-36,APOBEC2B,MSRB1,RNF113B,TRPS1 |
| quinone binding | VKORC1L1,AOC3,AMOTL1,HHIPL1,VKORC1,HHIP,NDUFS2,HHIPL2,AOC2,AOC1 |
| protein homodimerization activity | BCL2A1,CD2,MIXL1,RBM11,NR6A1A,WRN,ADH5,AGXT,Bcl2a1b,CBX5 |
| copper ion binding | HEPHL1,METTL17,S100V2,MOXD1,LOXL5A,ATP7B,S100A5,PARK7,ANG,LOX |
| drug binding | CHRM3,PDE4D,IL2RA,HTR2C,UGT1A7,P2RX4,HTR2B,ADRB2,DHFR,NAMPT |
| calcium ion binding | PCDHB2,CLEC3B,CD248A,MYL12B,DOC2D,CMLC1,CACNA1SA,PLSCR2,PCDHGA8,GUCA1B |
| heparin binding | WISP2,CHRD,PCOLCE2,CECR1,LIPI,ANG,OVALX,SLIT1,ZFP207,IMPG2 |
| primary amine oxidase activity | VCAM1,AOC3,AOC1,MAOA,MAOB,AOC2 |
Interacting Protein
ABP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABP1.
Resources
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References
- Grandits, M; Oostenbrink, C; et al. Molecular dynamics simulations of the auxin-binding protein 1 in complex with indole-3-acetic acid and naphthalen-1-acetic acid. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 82:2744-2755(2014).
- Seeley-Fallen, MK; Liu, LJ; et al. Actin-binding protein 1 links B-cell antigen receptors to negative signaling pathways. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:9881-9886(2014).
