ABCC9

  • Official Full Name

    ATP-binding cassette, sub-family C (CFTR/MRP), member 9

  • Overview

    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants.

  • Synonyms

    ABCC9;ATP-binding cassette, sub-family C (CFTR/MRP), member 9;SUR2;ABC37;CANTU;CMD1O;ATFB12

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • Rat
  • E.coli
  • Mammalian Cells
  • E.Coli/Yeast
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
RAB26-2110H Recombinant Human RAB26 protein, His-tagged E.coli Human His 1-256 aa
ABCC9-3267Z Recombinant Zebrafish ABCC9 Mammalian Cells Zebrafish His
ABCC9-3732H Recombinant Human ABCC9, His-tagged E.Coli/Yeast Human His 1549
Abcc9-3734M Recombinant Mouse Abcc9, His-tagged E.Coli/Yeast Mouse His 1533
ABCC9-409R Recombinant Rat ABCC9 Protein Mammalian Cells Rat His
ABCC9-64R Recombinant Rat ABCC9 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ABCC9-64R-B Recombinant Rat ABCC9 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    ABCC9 involved in several pathways and played different roles in them. We selected most pathways ABCC9 participated on our site, such as ABC transporters,ABC-family proteins mediated transport,ATP sensitive Potassium channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCC9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ATP sensitive Potassium channels KCNJ8,KCNJ11
    ABC transporters CFTR,ABCA8,ABCD2,ABCD3A,ABCB10,ABCC4,ABCC6,ABCG2,ABCG1,ABCC2
    Potassium Channels KCNC2,KCNK6,KCNC3A,KCNN4,KCND3,KCNA7,KCNQ1,KCNG4A,KCNN3,KCNK13A
    ABC-family proteins mediated transport EIF2S1,ABCA4A,EIF2S1A,ABCG4B,ABCB8,EIF2S3,ABCC2,ABCE1,CFTR,APOA1B
    Inwardly rectifying K+ channels KCNJ1,KCNJ15,KCNJ2A,GNGT2B,KCNJ1A.6,KCNJ1A.2,KCNJ14,KCNJ10,KCNJ1A.5,KCNJ11
    Neuronal System KCNK2B,KCNJ1A.4,KCNQ3,ARL6IP5,CHRNA1,GLS2B,KCNG1,KCNC1B,CHRNA3,KCNJ11
    Transmembrane transport of small molecules SLC12A7,ADD2,SLC35B2,SLC43A2A,ATP13A1,MFSD7B,ABCE1,ASPH,CLCNKA,AZGP1

    Protein Function

    ABCC9 has several biochemical functions, for example, ATP binding,ATPase activity, coupled to transmembrane movement of substances,ion channel binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCC9 itself. We selected most functions ABCC9 had, and list some proteins which have the same functions with ABCC9. You can find most of the proteins on our site.

    Function Related Protein
    potassium channel regulator activity AMIGO1,KCNMB3,ARPP19A,PRKCZ,DRD4,ADRB2,KCNMB2,KCNS3,KCNV1,KCNE3
    transporter activity PTGDSB,SYPA,PDZK1,SLC4A8,SYPL2B,ABCB10,TCIRG1,FABP7B,SLC22A23,AQP11
    potassium channel activity KCNA2B,KCNIP3,TRPM5,KCNK5B,KCNK18,KCNK10,KCNK3,KCNIP4,KCNA2,KCNF1A
    ATPase activity, coupled to transmembrane movement of substances ABCB6,ABCA13,ABCB6A,ABCC12,ABCG5,ABCD2,ABCC6,IPO8,ABCC1,ABCG2
    ion channel binding AKAP9,YES1,CHERP,DLG1,FGF12,SLC14A2,KCNQ3,PKD1,FKBP1A,PPP1R9B
    ATP binding TRP53,JAK2A,ACTB2,MYH1B,TRAP1,RPS6KB1,PAK2B,ABCD4,NLRP4E,KIF22
    sulfonylurea receptor activity ABCC8

    Interacting Protein

    ABCC9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCC9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCC9.

    KCNJ11

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