Random Mutagenesis

The GenePower^TM Controlled Randomization technology allows you to accurately direct the effective frequency of random nucleotide substitutions. And unlike error-prone PCR, you decide exactly which part(s) of the gene are affected—randomize the entire open reading frame or confine the mutagenesis to specific regions.

Chemical-based mutagenesis
With chemical based mutagenesis, we provide you with a convenient and cheap mutagenesis method for the generation of low mutation frequency libraries.

Biological-based mutagenesis
With our mutator strain library, we provide you with an approximately higher mutation rate strategy with the specific DNA.

Site-Saturation Mutagenesis
Site-Saturation Mutagenesis Service at Creative BioMart systematically replaces WT amino acid coding sequences with all 19 non-wild type amino acids at the position(s) you specify. Well-known as sequential permutation, site-saturation mutagenesis in combination with a powerful screening assay is the most systematic mutation strategy to identify amino acid substitutions that fulfill your protein engineering goals.