ZW10
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Official Full Name
ZW10, kinetochore associated, homolog (Drosophila) -
Overview
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. -
Synonyms
ZW10;ZW10, kinetochore associated, homolog (Drosophila);ZW10 (Drosophila) homolog, centromere/kinetochore protein;centromere/kinetochore protein zw10 homolog;KNTC1AP;Centromere/kinetochore protein zw10;HZW 10;HZW10;Kinetochore associated homolog;MGC149821;Zeste white 10;Zeste white 10 homolog;ZW 10;ZW 10 homolog centromere/kinetochore protein;ZW 10 kinetochore associated homolog;ZW10 (Drosophila) homolog centromere/kinetochore protein;ZW10 homolog centromere/kinetochore protein (Drosophila);ZW10 homolog centromere/kinetochore protein;ZW10 kinetochore associated homolog;ZW10_HUMAN;OTTHUMP00000238248;OTTHUMP00000238249;ZW10 homolog, centromere/kinetochore protein
Recombinant Proteins
- Zebrafish
- Mouse
- Chicken
- Rat
- Human
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZW10-10491Z | Recombinant Zebrafish ZW10 | Mammalian Cell | Zebrafish | His |
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| ZW10-19256M | Recombinant Mouse ZW10 Protein | Mammalian Cell | Mouse | His |
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| ZW10-6152C | Recombinant Chicken ZW10 | Mammalian Cell | Chicken | His |
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| ZW10-6720R | Recombinant Rat ZW10 Protein | Mammalian Cell | Rat | His |
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| ZW10-2102HCL | Recombinant Human ZW10 cell lysate | Human | Non |
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| ZW10-10510M | Recombinant Mouse ZW10 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ZW10-10510M-B | Recombinant Mouse ZW10 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ZW10-1065H | Recombinant Human ZW10 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| ZW10-6376R | Recombinant Rat ZW10 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ZW10-6376R-B | Recombinant Rat ZW10 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Zw10-7132M | Recombinant Mouse Zw10 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ZW10-762H | Recombinant Human ZW10 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
ZW10 involved in several pathways and played different roles in them. We selected most pathways ZW10 participated on our site, such as Cell Cycle, Mitotic,M Phase,Mitotic Anaphase, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZW10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic Prometaphase | SMC2,SPDL1,ZWILCH,SPC25,DSN1,RCC2,RANGAP1B,PANE1,PDS5A,CDCA5 |
| Mitotic Anaphase | MIS12,CENPE,SPC25,CDCA8,CCDC99,CENPN,MLF1IP,CENPC1,VRK2,ZWINT |
| RHO GTPase Effectors | RTKN,KTN1,WIPF3,RCC2,PMF1,SKA1,IQGAP3,KIF14,ABI1A,FMNL1 |
| Cell Cycle, Mitotic | NEK6,HIST3H2BB,MLF1IP,CP110,NEDD1,NCAPD3,DCTN1A,CEP63,CSNK2B,SKA1 |
| Mitotic Metaphase and Anaphase | NDEL1B,ITGB3BP,AHCTF1,MIS12,CDCA8,SPC24,VRK2,CENPO,CENPN,SPC25 |
| M Phase | KIF2A,ZWINT,CENPP,MASTL,ENSA,PHF8,ARPP19,LEMD3,NCAPH,STAG1 |
| RHO GTPases Activate Formins | RHOAE,NDEL1A,SKA1,RCC2,NSL1,SPC25,SPDL1,DSN1,CLIP1,AHCTF1 |
Protein Function
ZW10 has several biochemical functions, for example, centromeric DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZW10 itself. We selected most functions ZW10 had, and list some proteins which have the same functions with ZW10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| centromeric DNA binding | CENPB,MLH3,KIF2C,CENPC1,MSH3,MSH2 |
| protein binding | UBAP1,PLEKHG4,OLFM2,SMARCAL1,ETV6,C1orf21,SNRPB,KRT80,ZBTB48,TERF1 |
Interacting Protein
ZW10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZW10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZW10.
RINT1;ZWINT;NBAS
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References
- Bremner, KH; Scherer, J; et al. Adenovirus Transport via Direct Interaction of Cytoplasmic Dynein with the Viral Capsid Hexon Subunit. CELL HOST & MICROBE 6:523-535(2009).
- Yee, JC; Gatti, MD; et al. Genomic and proteomic exploration of CHO and hybridoma cells under sodium butyrate treatment. BIOTECHNOLOGY AND BIOENGINEERING 99:1186-1204(2008).
