ZNF397
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Official Full Name
zinc finger protein 397 -
Overview
This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined. -
Synonyms
ZNF397;zinc finger protein 397;zinc finger protein 47 , ZNF47;MGC13250;ZSCAN15;zinc finger protein 47;zinc finger and SCAN domain-containing protein 15;ZNF47;AI461664;2810411K16Rik;6720480F11Rik
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZNF397-3846H | Recombinant Human ZNF397, His-tagged | E.coli | Human | His | 1-275aa | |
| ZNF397-5329R | Recombinant Rhesus monkey ZNF397 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| ZNF397-78HCL | Recombinant Human ZNF397 293 Cell Lysate | HEK293 | Human | Non |
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| Zfp397-7090M | Recombinant Mouse Zfp397 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ZNF397-2374H | Recombinant Human ZNF397 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| ZNF397-5142R | Recombinant Rhesus Macaque ZNF397 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ZNF397-5142R-B | Recombinant Rhesus Macaque ZNF397 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
ZNF397 involved in several pathways and played different roles in them. We selected most pathways ZNF397 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF397 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ZNF397 has several biochemical functions, for example, metal ion binding,protein binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF397 itself. We selected most functions ZNF397 had, and list some proteins which have the same functions with ZNF397. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | NKX6-2,HOXA3,MEF2A,MYCLB,DBPB,TADA2B,XBP1,PAX8,MYT1LA,TGIF2 |
| metal ion binding | PRKD1,MOB1A,BTR22,DMRTA2,GALNT11,ALPL,UQCRFS1,TATDN3,HE2,CLCA3 |
| sequence-specific DNA binding | ATF7,MAFG,NR4A2B,MNX1,ZFP536,GRHL2A,ZNF232,TP53,RORC,EVX2 |
| protein binding | TNK1,IRS4,CKMT1,ITGB1BP1,TRIM59,SEMA6A,TDP2,CHAMP1,IFITM3,CHD2 |
Interacting Protein
ZNF397 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF397 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF397.
PRKAA2;LMO4;ZNF410;ZNF446
Resources
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References
- Zhang, Y; Hu, W; et al. Cysteine 397 plays important roles in the folding of the neuron-restricted silencer factor/RE1-silencing transcription factor. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 414:309-314(2011).
- Liu, JL; Rigolet, P; et al. The zinc finger motif of Escherichia coli RecQ is implicated in both DNA binding and protein folding. JOURNAL OF BIOLOGICAL CHEMISTRY 279:42794-42802(2004).
