ZHX1

  • Official Full Name

    zinc fingers and homeoboxes 1

  • Overview

    The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene.

  • Synonyms

    ZHX1;zinc fingers and homeoboxes 1;zinc fingers and homeoboxes protein 1;ZHX 1;ZHX-1;ZHX1_HUMAN;Zinc finger and homeodomain protein 1;Zinc fingers and homeobox 1;OTTHUMP00000228386;OTTHUMP00000228389

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • Rat
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
ZHX1-3809H Recombinant Human ZHX1, GST-tagged E.coli Human GST 16-307aa
ZHX1-19173M Recombinant Mouse ZHX1 Protein Mammalian Cells Mouse His
ZHX1-5292R Recombinant Rhesus monkey ZHX1 Protein, His-tagged Mammalian Cells Rhesus macaque His
ZHX1-6706R Recombinant Rat ZHX1 Protein Mammalian Cells Rat His
ZHX1-1982HCL Recombinant Human ZHX1 cell lysate Human Non
ZHX1-10377M Recombinant Mouse ZHX1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ZHX1-10377M-B Recombinant Mouse ZHX1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
ZHX1-5105R Recombinant Rhesus Macaque ZHX1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
ZHX1-5105R-B Recombinant Rhesus Macaque ZHX1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ZHX1-6338R Recombinant Rat ZHX1 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
ZHX1-6338R-B Recombinant Rat ZHX1 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    ZHX1 involved in several pathways and played different roles in them. We selected most pathways ZHX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZHX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    ZHX1 has several biochemical functions, for example, DNA binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZHX1 itself. We selected most functions ZHX1 had, and list some proteins which have the same functions with ZHX1. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding SOX15,SPTY2D1,PGR,ZNF483,KCNH7,TBX3A,RUNX1T1,SUB1A,ZSCAN5A,NR2F1A
    transcription corepressor activity CBFA2T3,TMEM38A,CDYL,TFCP2L1,NEUROD2,PRMT5,CTBP2,CTCF,CTBP2A,TLE2
    metal ion binding ZNF468,ATF7,BCL6A,GLIS1,ZFP28,INSM2,ACAP1,ALOX5B.2,ZFP804A,OVOL1
    protein binding BAIAP2L1,NTS,SYNJ2BP,PSMD11,PSMA1,EBF2,CENPJ,CNNM3,RBM42,OSBP2
    protein heterodimerization activity IKBKB,BCL11A,ITGA3,RARA,CAPN2,CHUK,DDX1,HIST1H3F,TFAP2B,NPM1
    transcription factor activity, sequence-specific DNA binding FOXN2B,FOXP3A,RORCB,GABPA,ZNF624,ZFP146,SOX4,TFAM,NFYC,SOX5

    Interacting Protein

    ZHX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZHX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZHX1.

    DNMT3B;ZHX2;ATXN1;NR3C1;PSMD11;BHLHE40;TNFRSF10C;PEX14;PRPF40A;IDH1

    Resources

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