ZNF346
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Official Full Name
zinc finger protein 346 -
Overview
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. -
Synonyms
ZNF346;zinc finger protein 346;JAZ;Zfp346;DKFZp547M223;Double stranded RNA binding zinc finger protein;Double stranded RNA binding zinc finger protein JAZ;Just another zinc finger protein;ZN346_HUMAN;OTTHUMP00000161434;OTTHUMP00000223533;OTTHUMP00000223535;OTTHUMP00000223537;double-stranded RNA-binding zinc finger protein JAZ
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
- SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZNF346-3841H | Recombinant Human ZNF346, GST-tagged | E.coli | Human | GST | 1-294aa | |
| ZFP346-18897M | Recombinant Mouse ZFP346 Protein | Mammalian Cells | Mouse | His |
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| ZNF346-2306H | Recombinant Human ZNF346, His-tagged | E.coli | Human | His | 317aa |
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| ZNF346-5203Z | Recombinant Zebrafish ZNF346 | Mammalian Cells | Zebrafish | His |
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| ZNF346-2016HCL | Recombinant Human ZNF346 cell lysate | Human | Non |
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| Zfp346-7085M | Recombinant Mouse Zfp346 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| ZNF346-10416M | Recombinant Mouse ZNF346 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ZNF346-10416M-B | Recombinant Mouse ZNF346 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ZNF346-1782M | Recombinant Mouse ZNF346 Protein (1-294 aa), His-SUMO-tagged | E.coli | Mouse | His&SUMO | 1-294 aa |
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Involved Pathway
ZNF346 involved in several pathways and played different roles in them. We selected most pathways ZNF346 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF346 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ZNF346 has several biochemical functions, for example, double-stranded RNA binding,enzyme binding,p53 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF346 itself. We selected most functions ZNF346 had, and list some proteins which have the same functions with ZNF346. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SERPINF2,ANGPT2,IL17RA,EIF2B4,HSPA4L,TAF3,GPX7,NOTCH4,RPAP3,PDGFA |
| zinc ion binding | MORC3B,FTR82,PRICKLE1A,RFPL3,NEURL1AA,TRIM31,MT1M,PDZRN3,MEX3C,USP22 |
| poly(A) RNA binding | CCDC137,MRPS14,RPP25L,FASTKD5,HDLBP,ADK,MRPL42,BUD13,SFRS9,EWSR1 |
| double-stranded RNA binding | APTX,OAS2,ZFP346,OASL1,DROSHA,IFIH1,DDX21,CLTC,ELAVL1,TUBA1B |
| p53 binding | AAAS,TP53BP1,EHMT2,ZFP346,RFWD3,RNF34,ZNF385A,BRD4,SETD7,ZNF385D |
| enzyme binding | YWHAE,TBP,SELS,KIAA1967,TH,ATF7,ITGB3,SORT1,PPP3CA,HAND2 |
Interacting Protein
ZNF346 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF346 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF346.
TARBP2;EIF2AK2;PB1;NS;NS;ANKHD1;Ccdc9;pre-let-7a;Sod1;NS;Rpl35;THOC2;Klc2;Lima1
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