YTHDC2
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Official Full Name
YTH domain containing 2 -
Synonyms
YTHDC2;YTH domain containing 2;24721;ENSG00000047188;5q22.2;probable ATP-dependent RNA helicase YTHDC2;probable ATP-dependent RNA helicase YTHDC2;EC 3.6.4.13
Recombinant Proteins
- Mouse
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- GST
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| YTHDC2-18678M | Recombinant Mouse YTHDC2 Protein | Mammalian Cells | Mouse | His |
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| YTHDC2-012H | Recombinant Human YTH N6-methyladenosine RNA binding protein C2 Protein, His tagged | E.coli | Human | His | 1286-1430aa |
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| YTHDC2-052H | Recombinant Human YTHDC2 Protein, GST-tagged | E.coli | Human | GST | 1288-1421 |
|
| YTHDC2-10267M | Recombinant Mouse YTHDC2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| YTHDC2-10267M-B | Recombinant Mouse YTHDC2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| YTHDC2-20H | Recombinant Human YTHDC2 Protein, GST-tagged | E.coli | Human | GST | 1288-1421 |
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| YTHDC2-301175H | Recombinant Human YTHDC2 protein, GST-tagged | E.coli | Human | GST | His1131-Asp1430 |
|
Involved Pathway
YTHDC2 involved in several pathways and played different roles in them. We selected most pathways YTHDC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with YTHDC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
YTHDC2 has several biochemical functions, for example, ATP binding,ATP-dependent RNA helicase activity,RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YTHDC2 itself. We selected most functions YTHDC2 had, and list some proteins which have the same functions with YTHDC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleic acid binding | ENOX1,REV3L,CPEB1A,GPKOW,ZFP746,ZFP14,ZNF710A,PABPC1A,RNASE7,CIZ1B |
| poly(A) RNA binding | MRPL9,NTPCR,DDX42,RALY,HIST1H4M,LARP7,MBNL2,SEC23IP,RPL23A,AHNAK |
| nucleotide binding | MAPKAPK2B,PTK6B,PET112L,TNIKB,CAMK1DB,TMEM63B,GNAI2A,OXSR1B,RAB35B,SGK2A |
| RNA polymerase binding | PHRF1,PPIB,PKN2,RRN3,STOM,NEDD4,TAF10,ANP32B,BIN1,GSG1 |
| ATP-dependent RNA helicase activity | DHX33,DDX39B,DDX17,EIF4A1B,DDX39AA,G3BP1,DHX16,EIF4A1A,DDX25,DHX35 |
| helicase activity | EIF4A1A,GTF2F2A,HELQ,HLTF,UPF1,SMARCA4,MCM9,BAT1,DNA2,GTF2F2B |
| RNA binding | SMN2,RPS9,PTBP2A,PUS3,OASL1,DDX59,SNRPE,APOBEC1,DPPA5,ADARB1A |
| hydrolase activity | TDRD9,ACY3.1,MBLAC1,CAPN2L,TMPRSS4B,PDE5AB,GTF2F2B,KLK1B22,DHX57,PTPN2B |
| ATP binding | PKLR,MVD,CHD1,PRKG1,XYLB,MKI67,SARS,UBE2H,FUK,MAP2K4A |
Interacting Protein
YTHDC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YTHDC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of YTHDC2.
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References
- Tanabe, A; Konno, J; et al. Transcriptional machinery of TNF-alpha-inducible YTH domain containing 2 (YTHDC2) gene. GENE 535:24-32(2014).
- Yang, Y; Sun, BF; et al. Dynamic m(6)A modification and its emerging regulatory role in mRNA splicing. SCIENCE BULLETIN 60:21-32(2015).
