WIPI2
-
Official Full Name
WD repeat domain, phosphoinositide interacting 2 -
Overview
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of;multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein;interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller;structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 (PubMed;15602573)). -
Synonyms
WIPI2;WD repeat domain, phosphoinositide interacting 2;WD repeat domain phosphoinositide-interacting protein 2;ATG18B;Atg21;CGI 50;DKFZP434J154;DKFZp686P02188;FLJ12979;FLJ14217;FLJ42984;WIPI49-like protein 2;WD40 repeat protein interacting wit
Recombinant Proteins
- Chicken
- Mouse
- Rat
- Zebrafish
- Human
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WIPI2-1313C | Recombinant Chicken WIPI2 | Mammalian Cells | Chicken | His |
|
|
| WIPI2-18554M | Recombinant Mouse WIPI2 Protein | Mammalian Cells | Mouse | His |
|
|
| WIPI2-6593R | Recombinant Rat WIPI2 Protein | Mammalian Cells | Rat | His |
|
|
| WIPI2-827Z | Recombinant Zebrafish WIPI2 | Mammalian Cells | Zebrafish | His |
|
|
| WIPI2-309HCL | Recombinant Human WIPI2 293 Cell Lysate | HEK293 | Human | Non |
|
|
| WIPI2-10182M | Recombinant Mouse WIPI2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| WIPI2-10182M-B | Recombinant Mouse WIPI2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| WIPI2-6249R | Recombinant Rat WIPI2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| WIPI2-6249R-B | Recombinant Rat WIPI2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
Involved Pathway
WIPI2 involved in several pathways and played different roles in them. We selected most pathways WIPI2 participated on our site, such as Cellular responses to stress,Macroautophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with WIPI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cellular responses to stress | CHMP4B,TERF2,HIST1H1E,EGLN2,ACD,ATG7,CDKN2C,HIST3H2BB,ATG4A,AMBRA1B |
| Macroautophagy | GABARAPL2,RB1CC1,DYNLL2A,MAP1LC3B,WDR45L,LC3,DYNLL2B,MAP1LC3C,ULK1A,WIPI1 |
Protein Function
WIPI2 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate binding,phosphatidylinositol-3-phosphate binding,phosphatidylinositol-5-phosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WIPI2 itself. We selected most functions WIPI2 had, and list some proteins which have the same functions with WIPI2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylinositol-3-phosphate binding | ZFYVE26,WDR45L,WDR45B,SNX13,JPH2,ZFYVE19,PLEKHF1,SNX24,SNX27,BBS5 |
| phosphatidylinositol-3,5-bisphosphate binding | WDR45B,RS1,CLVS2,D6WSU116E,WDR45L,SNX14,COMMD1,KIF16B,SESTD1,SH3PXD2B |
| phosphatidylinositol-5-phosphate binding | FAM21C,PHLDA3,PLEKHF1,SESTD1,SNX3,LANCL2,D6WSU116E,SNX24,RS1,SH3PXD2B |
| protein binding | KLK8,FAM54B,NPM3,SYNE1,SPG21,INPP5B,PPP2R5C,PFN1,BMP7,PTPRN |
Interacting Protein
WIPI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WIPI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of WIPI2.
ARL6IP1;RABAC1;POT1;FLNC;BTBD8;NUDC;PFKP
Resources
Related Services
Related Products
References
