WIPF2
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Official Full Name
WAS/WASL interacting protein family, member 2 -
Overview
This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery. -
Synonyms
WIPF2;WAS/WASL interacting protein family, member 2;WAS/WASL-interacting protein family member 2;WICH;WIRE;WIP-related protein;WASP-binding protein;WIP- and CR16-homologous protein;WASP-interacting protein-related protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WIPF2-3732H | Recombinant Human WIPF2, His-tagged | E.coli | Human | His | 18-176aa | |
| WIPF2-18551M | Recombinant Mouse WIPF2 Protein | Mammalian Cell | Mouse | His |
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| WIPF2-10181M | Recombinant Mouse WIPF2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| WIPF2-10181M-B | Recombinant Mouse WIPF2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
WIPF2 involved in several pathways and played different roles in them. We selected most pathways WIPF2 participated on our site, such as Endocytosis,Fcgamma receptor (FCGR) dependent phagocytosis,Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with WIPF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RHO GTPases Activate WASPs and WAVEs | ABI2,WASF3,WIPF3,ABI1B,ABI1A,NCKIPSD |
| RHO GTPase Effectors | RANGAP1B,RHOGA,RTKN,ERCC6L,PRC1,ABI1,RHOC,EVL,SGOL2,MIS12 |
| Endocytosis | AGAP2,SMAP2,GRK1B,HLA-C,LDLRAP1,ARF3A,FAM21A,SNX2,PML,RAB4A |
| Fcgamma receptor (FCGR) dependent phagocytosis | ABI2,ABI1B,MYO9B,ACTR2B,WASF2,ACTR2,NCKAP1,BAIAP2,PPAPDC1B,IgG3 |
| Immune System | LAIR2,DEFB106A,IgG3,HERC5,KIF2A,SIGLEC9,CLEC4D,DEFB119,DZIP3,LRRC41 |
| Innate Immune System | SUGT1,DEFB103A,BTR02,DDX41,CD300E,LAT2,MGC174155,TREX1,BTR18,PANX1B |
| Signal Transduction | RAMP1,IQGAP3,ACVR1C,PCSK6,CBY1,ARHGAP31,CDC42EP5,GPR68,ZNRF3,RTN4 |
| Regulation of actin dynamics for phagocytic cup formation | ABI1B,WIPF3,NCKIPSD,MYO1C,ABI1A,MYO9B |
Protein Function
WIPF2 has several biochemical functions, for example, actin filament binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WIPF2 itself. We selected most functions WIPF2 had, and list some proteins which have the same functions with WIPF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin filament binding | TMOD1,PPP1R9A,PLS1,DBNLA,SMYHC2,MYO1E,MYO1D,TTN,TRIOBPB,HAND2 |
| protein binding | NOTCH2NL,CRHR2,PAN3,RANGAP1,BNIP3,TMEM51,FAM131B,UBA52,ASGR2,HAUS1 |
Interacting Protein
WIPF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WIPF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of WIPF2.
GRB2;WWOX;WASL;WAS;lysR18;NCK1
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