WDR3

  • Official Full Name

    WD repeat domain 3
  • Overview

    This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.
  • Synonyms

    WDR3;WD repeat domain 3;WD repeat-containing protein 3;DIP2;FLJ12796;UTP12;dJ776P7.2 (WD repeat domain 3)

Recombinant Proteins

  • Mouse
  • Chicken
  • Rhesus macaque
  • Zebrafish
  • Mammalian Cell
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
WDR3-18463M Recombinant Mouse WDR3 Protein Mammalian Cell Mouse His
WDR3-3132C Recombinant Chicken WDR3 Mammalian Cell Chicken His
WDR3-5196R Recombinant Rhesus monkey WDR3 Protein, His-tagged Mammalian Cell Rhesus macaque His
WDR3-9863Z Recombinant Zebrafish WDR3 Mammalian Cell Zebrafish His
WDR3-10127M Recombinant Mouse WDR3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
WDR3-10127M-B Recombinant Mouse WDR3 Protein Pre-coupled Magnetic Beads HEK293 Mouse
WDR3-5009R Recombinant Rhesus Macaque WDR3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
WDR3-5009R-B Recombinant Rhesus Macaque WDR3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque

    Involved Pathway

    WDR3 involved in several pathways and played different roles in them. We selected most pathways WDR3 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ribosome biogenesis in eukaryotes EIF6,RIOK1,RPP38,NXT2,ACK2,DROSHA,RPP30,UTP6,LSG1,POP7

    Protein Function

    WDR3 has several biochemical functions, for example, poly(A) RNA binding,snoRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WDR3 itself. We selected most functions WDR3 had, and list some proteins which have the same functions with WDR3. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding EPPK1,AHNAK,DDX3X,RPS14,SND1,SRP54,U2SURP,YARS2,RPS24,FRG1
    snoRNA binding NUDT1,IMP4,HEATR1,NOP10,IMP3,DDX21,NUDT7,NUDT5,TBL3,NHP2

    Interacting Protein

    WDR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR3.

    Resources

    References

    • Saeki, M; Egusa, H; et al. Exosome-Bound WD Repeat Protein Monad Inhibits Breast Cancer Cell Invasion by Degrading Amphiregulin mRNA. PLOS ONE 8:-(2013).
    • Teng, YN; Liao, MH; et al. Expression of lrwd1 in mouse testis and its centrosomal localization. INTERNATIONAL JOURNAL OF ANDROLOGY 33:832-840(2010).

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