WDR19

  • Official Full Name

    WD repeat domain 19

  • Overview

    This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains six WD repeats, a clathrin heavy-chain repeat, and three transmembrane domains. This gene is conserved from C. elegans to human. It may participate in androgen-regulated signaling mechanisms or in the vesicular trafficking of androgen-regulated secretory processes. Alternatively spliced transcript variants encoding distinct isoforms have been reported but the full-length nature of one of these variants has not been defined.

  • Synonyms

    WDR19;WD repeat domain 19;WD repeat-containing protein 19;DYF 2;FLJ23127;IFT144;intraflagellar transport 144 homolog (Chlamydomonas);KIAA1638;ORF26;Oseg6;Pwdmp;DYF2;Intraflagellar transport 144 homolog;WD repeat containing protein 19;WD repeat membrane protein PWDMP;WDR19_HUMAN;OTTHUMP00000218257;DYF-2

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • E.coli
  • Mammalian Cell
  • HEK293
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
WDR19-3709H Recombinant Human WDR19, His-tagged E.coli Human His 1-353aa
WDR19-18456M Recombinant Mouse WDR19 Protein Mammalian Cell Mouse His
WDR19-5194R Recombinant Rhesus monkey WDR19 Protein, His-tagged Mammalian Cell Rhesus macaque His
WDR19-1925HCL Recombinant Human WDR19 cell lysate Human Non
WDR19-10121M Recombinant Mouse WDR19 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
WDR19-10121M-B Recombinant Mouse WDR19 Protein Pre-coupled Magnetic Beads HEK293 Mouse
WDR19-5007R Recombinant Rhesus Macaque WDR19 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
WDR19-5007R-B Recombinant Rhesus Macaque WDR19 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque

    Involved Pathway

    WDR19 involved in several pathways and played different roles in them. We selected most pathways WDR19 participated on our site, such as Assembly of the primary cilium,Hedgehog off state,Intraflagellar transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hedgehog off state KIF7,INTU,IFT52,IFT88,IFT122,MKS1,IFT172,RPGRIP1L,BBS13,TTC21B
    Intraflagellar transport C11orf60,KIF3C,IFT52,CLUAP1,DYF-1,RABL5,KIFAP3B,DYNLRB2,WDR34,OST4
    Signal Transduction ROPN1,MKS1,RDH12,PTHLHA,EVL,GPR65,NRP2,RGS18,OXER1,SOUL3
    Assembly of the primary cilium WDR35,PKD1,CCT5,KIFAP3,CLASP1,OST4,TRAF3IP1,TNPO1,DCTN3,TMEM67
    Signaling by Hedgehog SPOPL,BOC,HHAT,IFT172,TTC21B,EVC,SCUBE2,DZIP1,IFT122,WDR35
    Organelle biogenesis and maintenance RABL5,IFT20,MRPL50,MRPS31,SCLT1,MKKS,MRPL47,KIFAP3B,MRPS34,PROL1

    Protein Function

    WDR19 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by WDR19 itself. We selected most functions WDR19 had, and list some proteins which have the same functions with WDR19. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    WDR19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR19 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR19.

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