WBP2
-
Official Full Name
WW domain binding protein 2 -
Overview
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined. -
Synonyms
WBP2;WW domain binding protein 2;WW domain-binding protein 2;WBP 2;MGC18269;WBP-2
Recombinant Proteins
- Cynomolgus
- Mouse
- Zebrafish
- Rhesus macaque
- Chicken
- Rat
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- His&Myc
- Non
- His&Fc&Avi
Involved Pathway
WBP2 involved in several pathways and played different roles in them. We selected most pathways WBP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with WBP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
WBP2 has several biochemical functions, for example, RNA polymerase II core promoter sequence-specific DNA binding,RNA polymerase II transcription coactivator activity,chromatin DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WBP2 itself. We selected most functions WBP2 had, and list some proteins which have the same functions with WBP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter sequence-specific DNA binding | SOX3,NSD1,MITF,H2AFZ,SOX11,TCF7L2,TP53,H3F3B,NFIL3,GATA1 |
| chromatin DNA binding | HIST1H1E,THRA,EP300,ATOH1,GATA1,H2AFZ,SRF,PPARGC1A,HIST1H1B,GRHL1 |
| RNA polymerase II transcription coactivator activity | MED12,CITED4,ANKRD1,RERE,CITED2,PRRX1,MKL1,CREBBP,PITX2,SMARCA2 |
| protein binding | ARID3A,FAH,HECTD3,HSPG2,CEBPG,TDRD1,FAM103A1,STRADA,ILK,MS4A3 |
Interacting Protein
WBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of WBP2.
YAP1;WWTR1;MAGEA4;WWOX;CLEC4G;SEPT3;GABARAP
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References
- Hrdinka, M; Draber, P; et al. PRR7 Is a Transmembrane Adaptor Protein Expressed in Activated T Cells Involved in Regulation of T Cell Receptor Signaling and Apoptosis. JOURNAL OF BIOLOGICAL CHEMISTRY 286:19617-19629(2011).
- Conkright, JJ; Apsley, KS; et al. Nedd4-2-Mediated Ubiquitination Facilitates Processing of Surfactant Protein-C. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 42:181-189(2010).
