WBP11

  • Official Full Name

    WW domain binding protein 11
  • Overview

    This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
  • Synonyms

    WBP11;WW domain binding protein 11;WW domain-binding protein 11;NPWBP;SIPP1;splicing factor;PQBP1 and PP1 interacting;DKFZp779M1063;MGC94547;Npw38 binding protein;Npw38 binding protein NpwBP;SH3 domain binding protein SNP70;SNP70;Splicing factor PQBP1 and PP1 interacting;WBP 11;Npw38-binding protein NpwBP;SH3 domain-binding protein SNP70;splicing factor, PQBP1 and PP1 interacting;splicing factor that interacts with PQBP-1 and PP1;WBP-11

Recombinant Proteins

  • Zebrafish
  • Mouse
  • Rhesus macaque
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
WBP11-11680Z Recombinant Zebrafish WBP11 Mammalian Cells Zebrafish His
WBP11-18432M Recombinant Mouse WBP11 Protein Mammalian Cells Mouse His
WBP11-5186R Recombinant Rhesus monkey WBP11 Protein, His-tagged Mammalian Cells Rhesus macaque His
WBP11-6560R Recombinant Rat WBP11 Protein Mammalian Cells Rat His
WBP11-1920HCL Recombinant Human WBP11 cell lysate Human Non
WBP11-10109M Recombinant Mouse WBP11 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
WBP11-10109M-B Recombinant Mouse WBP11 Protein Pre-coupled Magnetic Beads HEK293 Mouse
WBP11-4999R Recombinant Rhesus Macaque WBP11 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
WBP11-4999R-B Recombinant Rhesus Macaque WBP11 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
WBP11-6216R Recombinant Rat WBP11 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
WBP11-6216R-B Recombinant Rat WBP11 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    WBP11 involved in several pathways and played different roles in them. We selected most pathways WBP11 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with WBP11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome SNRPA1,CHERP,RBM22,HSP70L,DHX38,HNRPKL,SR140,NHP2L1,SRSF5B,SF3B6

    Protein Function

    WBP11 has several biochemical functions, for example, WW domain binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WBP11 itself. We selected most functions WBP11 had, and list some proteins which have the same functions with WBP11. You can find most of the proteins on our site.

    Function Related Protein
    single-stranded DNA binding SSBP3B,SSBP4,SSBP3A,HMGB1,RTF1,XRCC2,CTC1,CNBPA,TSN,MCM6
    poly(A) RNA binding TMSB4X,ABCF1,ZAK,RBM4,HIST1H4J,BOP1,SUGP2,ZFP106,SNTB2,RBMX2
    protein binding DGKZ,SAFB,ZNF205,NEU2,ZGPAT,EPOR,RPS13,MYOD1,CHEK1,PIK3CG
    WW domain binding TRAF4,LITAF,NFE2,TCEAL8,TCEAL3,KIF20B,PPARG,NDFIP2,TRP63,TCEAL5
    protein phosphatase type 1 regulator activity PHACTR3A,PPP1R16A,KCNS1,PPP1R15A,PHACTR3,UBXN2A,PPP1R16B,PHACTR3B,PPP1R7,NSFL1C

    Interacting Protein

    WBP11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WBP11 here. Most of them are supplied by our site. Hope this information will be useful for your research of WBP11.

    GRB2;PQBP1;q99ib8-pro_0000045603;FYN;TESC;TRAF4;PPP1CA

    Resources

    References

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