WASF3
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Official Full Name
WAS protein family, member 3 -
Overview
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. -
Synonyms
WASF3;WAS protein family, member 3;wiskott-Aldrich syndrome protein family member 3;KIAA0900;SCAR3;WAVE3;Protein WAVE-3;Protein WAVE3;Verprolin homology domain containing protein 3;Verprolin homology domain-containing protein 3;WASF3_HUMAN;WASP family protein member 3;Wiskott Aldrich syndrome protein family member 3;OTTHUMP00000018160;WASP family Verprolin-homologous protein 3;Brush-1
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WASF3-18428M | Recombinant Mouse WASF3 Protein | Mammalian Cells | Mouse | His |
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| WASF3-5184R | Recombinant Rhesus monkey WASF3 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| WASF3-1919HCL | Recombinant Human WASF3 cell lysate | Human | Non |
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| WASF3-10107M | Recombinant Mouse WASF3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| WASF3-10107M-B | Recombinant Mouse WASF3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| WASF3-4997R | Recombinant Rhesus Macaque WASF3 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| WASF3-4997R-B | Recombinant Rhesus Macaque WASF3 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
WASF3 involved in several pathways and played different roles in them. We selected most pathways WASF3 participated on our site, such as Adherens junction,Choline metabolism in cancer,Fc gamma R-mediated phagocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with WASF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Choline metabolism in cancer | GRB2,PLD1,Pdgfa&Pdgfb,TSC2,WAS,PIK3R2,PDGFA,GPCPD1,PIK3CA,TSC1 |
| Immune System | RNF19B,DZIP3,CLEC4A,C1rb,ACTR1A,BAIAP2,GRAP2A,CSH1,LAIR2,CTSE |
| Fc gamma R-mediated phagocytosis | MARCKS,PLA2G4F,PIK3CD,PLA2G4D,LIMK2,GSN,PTPRC,RAF1,PIK3CB,ARPC5L |
| Adherens junction | PTPN1,EGFR,FER,PTBP3,RHOAA,WASL,CDC42,ACTN1,FGFR1,CSNK2B |
| RHO GTPases Activate WASPs and WAVEs | ABI1A,NCKIPSD,WIPF2,ABI2,WIPF3,ABI1B |
| RHO GTPase Effectors | RTKN,PRC1,NOXA1,TAX1BP3,KLC3,AHCTF1,LIN7B,KIF14,CDCA8,SPDL1 |
| Innate Immune System | DEFA3,FCN1,IRF2,FCN3,PELI1,CFHL1,BAIAP2,PANX1,CHST13,PPAPDC1A |
| Fcgamma receptor (FCGR) dependent phagocytosis | BAIAP2,NCKAP1,DOCK1,ACTR3,MYO9B,MYO1C,NCKIPSD,ACTR2,PPAPDC1A,ACTR2B |
Protein Function
WASF3 has several biochemical functions, for example, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WASF3 itself. We selected most functions WASF3 had, and list some proteins which have the same functions with WASF3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | TRPV4,MYH7B,EZR,PXK,PLS3,PFN1,LMOD2,MICAL2B,MYO1F,EVLB |
Interacting Protein
WASF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WASF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of WASF3.
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