WAPAL
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Official Full Name
wings apart-like homolog (Drosophila) -
Overview
Wings apart-like protein homolog is a protein that in humans is encoded by the WAPAL gene. -
Synonyms
WAPAL;wings apart-like homolog (Drosophila);KIAA0261;wings apart-like protein homolog;FOE;friend of EBNA2;WAPL;Friend of EBNA2 (Epstein Barr virus nuclear protein 2);Friend of EBNA2 protein;OTTHUMP00000020004;WAPL_HUMAN;Wings apart like homolog;Wings apart like homolog (Drosophila);friend of EBNA2 (Epstein-Barr virus nuclear protein 2)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WAPAL-3697H | Recombinant Human WAPAL, GST-tagged | E.coli | Human | GST | 1-402aa | |
| WAPAL-18423M | Recombinant Mouse WAPAL Protein | Mammalian Cells | Mouse | His |
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| WAPAL-4353C | Recombinant Chicken WAPAL | Mammalian Cells | Chicken | His |
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| WAPAL-1918HCL | Recombinant Human WAPAL cell lysate | Human | Non |
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| WAPAL-10103M | Recombinant Mouse WAPAL Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| WAPAL-10103M-B | Recombinant Mouse WAPAL Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
WAPAL involved in several pathways and played different roles in them. We selected most pathways WAPAL participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with WAPAL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | NEDD1,HDAC5,ANAPC1,NDE1,CLIP1,MCM2,RBL2,CDC23,GMNN,ARPP19A |
| M Phase | PDS5A,SMC2,ARPP19,GORASP1,ENSAB,ANKLE2,NUF2,SET,CENPQ,NIPBLB |
| Mitotic Metaphase and Anaphase | CENPL,PMF1,DSN1,NUF2,VRK1,SPDL1,NDEL1B,NDEL1,ZWILCH,MIS12 |
| Mitotic Anaphase | PDS5A,CENPN,DSN1,MIS12,B9D2,VRK2,CDCA5,CENPP,CENPO,ERCC6L |
| Cohesin Loading onto Chromatin | STAG2,PDS5B,NIPBL,PDS5A,NIPBLB,NIPBLA,STAG1,MAU2 |
| Cell Cycle, Mitotic | MIS12,NUMA1,PDS5B,AURKB,MCM8,TMPO,CETN2,CENPC1,CEP57,APITD1 |
| Mitotic Prometaphase | SPC24,MIS12,ZWINT,CENPL,CENPO,SKA2,SMC2,CCDC99,SGOL2,RCC2 |
| Establishment of Sister Chromatid Cohesion | PDS5B,PDS5A,STAG2,STAG1,CDCA5,ESCO1,ESCO2 |
Protein Function
WAPAL has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WAPAL itself. We selected most functions WAPAL had, and list some proteins which have the same functions with WAPAL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NLK,PRPF6,DENND2D,HBZ,HIST1H4H,HP1BP3,BAAT,BSX,ATP4B,ATP6V1C2 |
Interacting Protein
WAPAL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WAPAL here. Most of them are supplied by our site. Hope this information will be useful for your research of WAPAL.
SMC3;PDS5A
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References
- Dobie, KW; Kennedy, CD; et al. Identification of chromosome inheritance modifiers in Drosophila melanogaster. GENETICS 157:1623-1637(2001).
- Oikawa, K; Ohbayashi, T; et al. Expression of a novel human gene, Human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression. CANCER RESEARCH 64:3545-3549(2004).
