VPS45

  • Official Full Name

    vacuolar protein sorting 45 homolog (S. cerevisiae)

  • Overview

    Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.

  • Synonyms

    VPS45;vacuolar protein sorting 45 homolog (S. cerevisiae);vacuolar protein sorting 45A (yeast homolog) , vacuolar protein sorting 45A (yeast) , VPS45A, VPS45B;vacuolar protein sorting-associated protein 45;h vps45;H1;h-VPS45;H1VPS45;HGNC:14579;hlVps45;Leucocyte vacuolar protein sorting 45;OTTHUMP00000014482;Vacuolar protein sorting 45A (yeast homolog);Vacuolar protein sorting 45A;Vacuolar protein sorting 45B (yeast);VPS45_HUMAN;VPS45A;VPS45B;VPS54A;VSP45;VSP45A

Recombinant Proteins

  • Mouse
  • Chicken
  • Rat
  • Zebrafish
  • Human
  • Mammalian Cell
  • HEK293
  • HEK293T
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
VPS45-18379M Recombinant Mouse VPS45 Protein Mammalian Cell Mouse His
VPS45-3233C Recombinant Chicken VPS45 Mammalian Cell Chicken His
VPS45-6544R Recombinant Rat VPS45 Protein Mammalian Cell Rat His
VPS45-8184Z Recombinant Zebrafish VPS45 Mammalian Cell Zebrafish His
VPS45-384HCL Recombinant Human VPS45 293 Cell Lysate HEK293 Human Non
VPS45-10071M Recombinant Mouse VPS45 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
VPS45-10071M-B Recombinant Mouse VPS45 Protein Pre-coupled Magnetic Beads HEK293 Mouse
VPS45-6200R Recombinant Rat VPS45 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
VPS45-6200R-B Recombinant Rat VPS45 Protein Pre-coupled Magnetic Beads HEK293 Rat
Vps45-6943M Recombinant Mouse Vps45 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    VPS45 involved in several pathways and played different roles in them. We selected most pathways VPS45 participated on our site, such as Endocytosis,Factors involved in megakaryocyte development and platelet production,Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS45 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis ARR3B,RAB11FIP4A,ITCH,FOLR2,HSP70L,SNX5,ASAP2A,PARD6B,CDC42L2,CXCR4A
    Hemostasis MAFG,CBX5,ANXA2A,HRG,ABHD12,RAPGEF3,SLC7A10,MFN1,BSG,GATA2A
    Factors involved in megakaryocyte development and platelet production KDM1A,MYB,DOCK10,DOCK8,ZFPM1,KIF20A,HBBE1.1,KIF9,OSTN,HBG1

    Protein Function

    VPS45 has several biochemical functions, for example, molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS45 itself. We selected most functions VPS45 had, and list some proteins which have the same functions with VPS45. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ATMIN,CISH,BAAT,HSPB7,KLB,MFN1,HIST1H1E,ADORA1,DVL3,EDC4
    molecular_function SETD1B,CCDC85A,FHDC1,GM13306,CYSTM1,PRR15LB,ANKRD10B,ZNF200,TMEM30AA,BCORL1

    Interacting Protein

    VPS45 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS45 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS45.

    RBSN;BCAR3;IGF1R;PTPN1;PAX2;CASP8;RB1CC1;gtp;pi3p;ere_dna

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