VPS11
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Official Full Name
vacuolar protein sorting 11 homolog (S. cerevisiae) -
Overview
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. -
Synonyms
VPS11;vacuolar protein sorting 11 homolog (S. cerevisiae);vacuolar protein sorting 11 (yeast homolog);vacuolar protein sorting-associated protein 11 homolog;PEP5;RNF108;END1;HGNC:14583;hVPS11;RING finger protein 108;Vacuolar protein sorting 11 (yeast);Vacuolar protein sorting associated protein 11 homolog;Vacuolar protein sorting protein 11
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| VPS11-3669H | Recombinant Human VPS11, His-tagged | E.coli | Human | His | 689-941aa | |
| VPS11-18358M | Recombinant Mouse VPS11 Protein | Mammalian Cell | Mouse | His |
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| VPS11-30026TH | Recombinant Human VPS11, His-tagged | E.coli | Human | His | 651-941 a.a. |
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| VPS11-3599Z | Recombinant Zebrafish VPS11 | Mammalian Cell | Zebrafish | His |
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| VPS11-1911HCL | Recombinant Human VPS11 cell lysate | Human | Non |
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| VPS11-10058M | Recombinant Mouse VPS11 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| VPS11-10058M-B | Recombinant Mouse VPS11 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| VPS11-687H | Recombinant Human VPS11 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Vps11-6930M | Recombinant Mouse Vps11 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
VPS11 involved in several pathways and played different roles in them. We selected most pathways VPS11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
VPS11 has several biochemical functions, for example, nucleotide binding,protein binding,protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS11 itself. We selected most functions VPS11 had, and list some proteins which have the same functions with VPS11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleotide binding | VPRBP,RBM4B,DDX19,HNRNPDL,GTF2F2A,PDPK1B,NLRP4E,ACTR2A,NSFB,PABPN1 |
| zinc ion binding | KAT7A,MID1,LANCL1,MAN2A2,PHF21A,NANOS2,MMP1,MAN2A1,PHF1,RUNX1 |
| protein binding | CEACAM6,FAM76B,DRD4,SIP1,PEX6,DTNB,LNX1,TNFRSF12A,PARK2,cgr2b |
| protein domain specific binding | WNT5A,MLF1,RCC2,DVL2,IPCEF1,CHMP2A,GABRR1,TUBB,ODF1,DBNL |
| syntaxin binding | NAPAA,PTPN2,NAPG,SYT5B,VAMP2,CPLX4C,CAV1,SYT1A,SYT11B,STXBP5L |
Interacting Protein
VPS11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS11 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS11.
VPS18;VPS16;Vps33a;386682
Resources
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References
- Sato, TK; Rehling, P; et al. Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. MOLECULAR CELL 6:661-671(2000).
