VPREB1
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Official Full Name
pre-B lymphocyte 1 -
Overview
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. -
Synonyms
VPREB1;pre-B lymphocyte 1;immunoglobulin iota chain;CD179A;VpreB;CD179 antigen like family member A;IGI;IGVPB;Pre B lymphocyte 1;Protein VPreB1;V(pre)B protein;VPREB 1;VpreB protein;OTTHUMP00000199011;OTTHUMP00000199012;CD179 antigen-like family member A
Recombinant Proteins
- Mouse
- Human
- Rat
- Mammalian Cells
- E.coli
- HEK293
- His
- His&T7
- His&Fc&Avi
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| VPREB1-18355M | Recombinant Mouse VPREB1 Protein | Mammalian Cells | Mouse | His |
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| VPREB1-5648H | Recombinant Human VPREB1 protein, His & T7-tagged | E.coli | Human | His&T7 | Leu33~Met135 |
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| Vpreb1-5649M | Recombinant Mouse Vpreb1 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Leu43~Glu134 |
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| Vpreb1-5650R | Recombinant Rat Vpreb1 protein, His & T7-tagged | E.coli | Rat | His&T7 | Leu43~Met128 |
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| VPREB1-0913H | Recombinant Human VPREB1 Protein (Leu33-Met135), N-His tagged | E.coli | Human | His | Leu33-Met135 |
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| VPREB1-10056M | Recombinant Mouse VPREB1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| VPREB1-10056M-B | Recombinant Mouse VPREB1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| VPREB1-3756H | Recombinant Human VPREB1 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 20-145aa |
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| VPREB1-5160H | Recombinant Human VPREB1 Protein (Met1-Pro145), C-His tagged | Mammalian Cells | Human | His | Met1-Pro145 |
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Involved Pathway
VPREB1 involved in several pathways and played different roles in them. We selected most pathways VPREB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPREB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
VPREB1 has several biochemical functions, for example, protein binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VPREB1 itself. We selected most functions VPREB1 had, and list some proteins which have the same functions with VPREB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activity | TREML2,MED12,VMN1R49,NEO1,PLXNA1,NRXN3,GRIN2A,CD200,SMAGP,ITGB3B |
| protein binding | FEZ1,MIEF1,ZNF625,PSMD9,Cd79a,GSDMD,MED22,HSD17B14,CPNE7,IRF9 |
Interacting Protein
VPREB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPREB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPREB1.
Resources
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References
- Dul, JL; Argon, Y; et al. The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development. EUROPEAN JOURNAL OF IMMUNOLOGY 26:906-913(1996).
