VAMP8
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Official Full Name
vesicle-associated membrane protein 8 (endobrevin) -
Overview
This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane. -
Synonyms
VAMP8;vesicle-associated membrane protein 8 (endobrevin);vesicle-associated membrane protein 8;EDB;Endobrevin;VAMP 8;VAMP-8;VAMP8_HUMAN;Vesicle associated membrane protein 8
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Rat
- Mus musculus
- E. coli
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- HEK293T
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
- His&GST
Involved Pathway
VAMP8 involved in several pathways and played different roles in them. We selected most pathways VAMP8 participated on our site, such as SNARE interactions in vesicular transport,Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with VAMP8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Platelet activation | ACTB,ITGB1,PLCB4,PLCB2,PRKACB,MYLK3,AKT1,RAP1B,ITPR3,ROCK2 |
| SNARE interactions in vesicular transport | STX11A,GOSR2,GOSR1,STX4A,STX4,SNAP23,BET1,STX5AL,GS15,STX11B.1 |
Protein Function
VAMP8 has several biochemical functions, for example, SNAP receptor activity,SNARE binding,chloride channel inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VAMP8 itself. We selected most functions VAMP8 had, and list some proteins which have the same functions with VAMP8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chloride channel inhibitor activity | WNK1,STX8,STX1A,STX7,CFTR,VTI1B |
| SNAP receptor activity | VAMP1,STX16,STX3A,STX5AL,STX11A,GOSR2,BET1L,GOSR1,SNAP25B,STX5A |
| protein binding | IFIT3,LPXN,ACTR8,PPP2R5E,SMYD1,CUTA,C16orf87,ADAM12,COX5A,CACNB2 |
| SNARE binding | STX1A,UNC13A,SYBL1,EXOC3L1,STX3A,STX5AL,STX1B,GABARAPL2,ANKRD27,CCDC167 |
Interacting Protein
VAMP8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VAMP8 here. Most of them are supplied by our site. Hope this information will be useful for your research of VAMP8.
STX17;Snap25;STX4;SNAP47;CDC25A;MLH1;UBE2G2;PNN;pi3p;STX7;STX6;SNAP29
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