VAMP3
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Official Full Name
vesicle-associated membrane protein 3 -
Overview
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008] -
Synonyms
VAMP3;vesicle-associated membrane protein 3;CEB;VAMP-3;cellubrevin;synaptobrevin-3
Recombinant Proteins
- Human
- Cynomolgus
- Zebrafish
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cells
- HEK293
- Mouse
- GST
- His
- Non
- Avi
- Fc
Involved Pathway
VAMP3 involved in several pathways and played different roles in them. We selected most pathways VAMP3 participated on our site, such as SNARE interactions in vesicular transport,Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with VAMP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SNARE interactions in vesicular transport | STX5AL,SNAP29,VAMP5,BET1,STX11A,STX5,BET1L,STX10,SYBL1,STX11 |
| Phagosome | CD14,ATPV0E2,THBS3A,STX7,TUBA8,TFRC,CCDC102A,ATP6V1G2,ITGB3,SEC61AL2 |
Protein Function
VAMP3 has several biochemical functions, for example, SNAP receptor activity,SNARE binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VAMP3 itself. We selected most functions VAMP3 had, and list some proteins which have the same functions with VAMP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RCN2,RTN4RL2B,XPO1,BLOC1S1,MAF,CTNNA2,ZNF193,FBXO46,SIVA1,AIDA |
| syntaxin-1 binding | NSF,STXBP3A,SNPH,CPLX1,UNC13A,SLC6A4,STXBP3,SYBU,CCDC167,MYO5A |
| SNARE binding | CCDC167,EXOC3L4,VAMP7,STX4,VAMP5,TRIM9,SEC22A,GOSR1,SEC22BA,STX5A |
| SNAP receptor activity | GS15,GOSR1,STX5,VAMP8,SNAP25,SEC22C,VTI1A,STX3A,SEC22A,SNAP25B |
Interacting Protein
VAMP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VAMP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of VAMP3.
STX4;SNAP23;Picalm;BCL2L13;Snap25;SNAP47;NELFE;DDB1;pi3p;STX7
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