UQCRC1
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Official Full Name
ubiquinol-cytochrome c reductase core protein I -
Overview
Cytochrome b-c1 complex subunit 1, mitochondrial is a protein that in humans is encoded by the UQCRC1 gene. -
Synonyms
UQCRC1;ubiquinol-cytochrome c reductase core protein I;cytochrome b-c1 complex subunit 1, mitochondrial;D3S3191;QCR1;UQCR1;mitochondrial;Complex III subunit 1;Core protein I;Cytochrome b c1 complex subunit 1, mitochondrial;Cytochrome b-c1 complex subunit 1;OTTHUMP00000164820;QCR1_HUMAN;Ubiquinol cytochrome c reductase core protein I;Ubiquinol-cytochrome-c reductase complex core protein 1
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
Involved Pathway
UQCRC1 involved in several pathways and played different roles in them. We selected most pathways UQCRC1 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with UQCRC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Huntingtons disease | SOD2,BAX,TGM2,COX6A2,POLR2J3,NDUFB7,ATP5H,UQCRFS1,HDAC2,DCTN4 |
| Alzheimers disease | NDUFA4,COX5B,NDUFV1,NDUFA7,NDUFC1,NCSTN,COX4I1,PLCB4,CAPN1,SNCA |
| Parkinsons disease | NDUFB10,PRKACG,NDUFA1,GNAI1,NDUFC1,ATP5D,MT-ATP6,NDUFS2,UQCR11,NDUFS1 |
| Non-alcoholic fatty liver disease (NAFLD) | PRKAA1,CEBPA,MLXIPL,ERN1,NDUFB8,PIK3R2,NDUFAB1,NDUFB9,NDUFA9,NDUFA2 |
| Oxidative phosphorylation | ATP6AP1B,ATP6V1H,NDUFS7,ATP12A,ATP6V0A1B,ATP6V0A1A,UQCRFS1,ATP6V0CB,Atp5k,ATP6V0A4 |
| Cardiac muscle contraction | COX7C,COX7A3,ATP1A3B,CACNB3A,ATP1B2A,CACNG1A,COX6A1,CACNG2,ATP1B1,VMHC |
| Metabolic pathways | TPI1B,PKLR,CHKB,ACAT1,AK5,ITPKB,CYP2B6,NAT,ST6GALNAC3,AOX3 |
Protein Function
UQCRC1 has several biochemical functions, for example, metalloendopeptidase activity,protein complex binding,ubiquinol-cytochrome-c reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UQCRC1 itself. We selected most functions UQCRC1 had, and list some proteins which have the same functions with UQCRC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | MMEL1,ADAM19,XRCC6BP1,MMP1A,ADAMTS2,C6AST3,ADAMTS3,ADAM30,TLL2,ADAM5P |
| protein complex binding | ATG101,VAMP2,GIT2,NCK2,ITPR1,RPTOR,HSPD1,UGT1A6B,TG,EP300 |
| zinc ion binding | FBXO30A,NR2F6,ZDHHC4,MBD1B,BMI1B,MICAL2,RNF125,RNF115,RNF181,GCH1 |
| ubiquinol-cytochrome-c reductase activity | UQCRFS1,UQCRH,UQCR10,UQCRQ,UQCR11 |
| ubiquitin protein ligase binding | GPR37,RRAGA,CUL9,AKTIP,TRIB2,PA2G4,PPARGC1A,PER1,YWHAE,MAP1LC3C |
Interacting Protein
UQCRC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UQCRC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UQCRC1.
UQCRC2;4505953;UQCRQ;UQCRB;DNAJA1;UQCRFS1;SNRPF;SMARCA2;UQCR10;RUVBL2;SRPRB;KRAS;TRIM63;NDUFS5
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