UPK1A
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Official Full Name
uroplakin 1A -
Overview
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. -
Synonyms
UPK1A;uroplakin 1A;uroplakin-1a;TSPAN21;UP1A;UPIA;UPKA;tspan-21;uroplakin Ia;tetraspanin-21
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Human
- Mouse
- Bovine
- Mus musculus
- Mammalian Cell
- E.coli
- HEK293
- E.coli expression system
- His
- His&T7
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UPK1A-3729Z | Recombinant Zebrafish UPK1A | Mammalian Cell | Zebrafish | His |
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| UPK1A-5109R | Recombinant Rhesus monkey UPK1A Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| UPK1A-7920H | Recombinant Human UPK1A protein, His & T7-tagged | E.coli | Human | His&T7 | His117~Gly232 |
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| Upk1a-7921M | Recombinant Mouse Upk1a protein, His & T7-tagged | E.coli | Mouse | His&T7 | His116~Gly231 |
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| UPK1A-723HCL | Recombinant Human UPK1A lysate | HEK293 | Human | Non |
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| RFL12149BF | Recombinant Full Length Bovine Uroplakin-1A(Upk1A) Protein, His-Tagged | E.coli expression system | Bovine | His | Full L. Full Length (1-258) |
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| RFL13422HF | Recombinant Full Length Human Uroplakin-1A(Upk1A) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-258) |
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| RFL30194MF | Recombinant Full Length Mouse Uroplakin-1A(Upk1A) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-257) |
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| UPK1A-4922R | Recombinant Rhesus Macaque UPK1A Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| UPK1A-4922R-B | Recombinant Rhesus Macaque UPK1A Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| UPK1A-5584H | Recombinant Human UPK1A Protein (His117-Gly232), N-His tagged | E.coli | Human | His | His117-Gly232 |
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Involved Pathway
UPK1A involved in several pathways and played different roles in them. We selected most pathways UPK1A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UPK1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
UPK1A has several biochemical functions, for example, monosaccharide binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UPK1A itself. We selected most functions UPK1A had, and list some proteins which have the same functions with UPK1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| monosaccharide binding | RPIA,FBP1,GPR19,GPI1,GPI,TALDO1,Siglece,PGLS |
| protein homodimerization activity | GRHPR,TDG,SMAD4,TIMELESS,UGT1A3,GSS,LRRK2,BMP4,UGT1A9,JAM3 |
Interacting Protein
UPK1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UPK1A here. Most of them are supplied by our site. Hope this information will be useful for your research of UPK1A.
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