ULK3
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Official Full Name
unc-51-like kinase 3 (C. elegans) -
Overview
Serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. May exert this function by promoting GLI1 nuclear localization. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. -
Synonyms
ULK3;unc-51-like kinase 3 (C. elegans);serine/threonine-protein kinase ULK3;DKFZP434C131;FLJ90566;ULK3_HUMAN;unc 51 like kinase 3 (C. elegans);Unc-51-like kinase 3
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Rat
- E.coli
- Sf10 Insect Cell
- Mammalian Cells
- Insect Cells
- HEK293
- Sf21 Cells
- His
- Non
- DDK&Myc
- Avi&Fc&His
- GST
Involved Pathway
ULK3 involved in several pathways and played different roles in them. We selected most pathways ULK3 participated on our site, such as Regulation of autophagy,mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ULK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mTOR signaling pathway | ULK1,AKT2,RPS6,PIK3R2,CAB39,PRKAA2,EIF4EA,PIK3CA,DDIT4,VEGFA |
| Regulation of autophagy | ATG10,ATG14,IFNA7,Ifna15,ATG12,ULK1,PIK3R4,IFNA2,INS,ATG4D |
Protein Function
ULK3 has several biochemical functions, for example, ATP binding,protein binding,protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ULK3 itself. We selected most functions ULK3 had, and list some proteins which have the same functions with ULK3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | TGFBR1B,ERBB3B,SLFNL1,PRKCHA,ABCG2B,MOS,RPS6KB1B,BMP2K,NUBP1,ATP5B |
| protein binding | GTF2H1,MAPK8IP3,ESYT2,KIR2DL1,RBBP4,RNF4,BARHL2,CYTH1,SAMM50,LIMS3L |
| protein serine/threonine kinase activity | BMP2K,PKZ,CSNK1G2B,ARAF,RAF1A,SQSTM1,CAMK2B1,MAST2,MAP2K4,MAP4K6 |
Interacting Protein
ULK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ULK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ULK3.
CDC37;pi3p;czc8004;linkable pd173955 analogue;linkable sunitinib analogue;linkable pelitinib analogue;bosutinib;imatinib;dasatinib;purvalanol b;midostaurin
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