UIMC1
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Official Full Name
ubiquitin interaction motif containing 1 -
Overview
BRCA1-A complex subunit RAP80 is a protein that in humans is encoded by the UIMC1 gene. -
Synonyms
UIMC1;ubiquitin interaction motif containing 1;BRCA1-A complex subunit RAP80;RAP80;receptor associated protein 80;receptor-associated protein 80;retinoid x receptor interacting protein;retinoid X receptor-interacting protein 110;ubiquitin interact
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UIMC1-17830M | Recombinant Mouse UIMC1 Protein | Mammalian Cells | Mouse | His |
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| UIMC1-6440R | Recombinant Rat UIMC1 Protein | Mammalian Cells | Rat | His |
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| UIMC1-506HCL | Recombinant Human UIMC1 293 Cell Lysate | HEK293 | Human | Non |
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| UIMC1-6096R | Recombinant Rat UIMC1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| UIMC1-6096R-B | Recombinant Rat UIMC1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| UIMC1-9901M | Recombinant Mouse UIMC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| UIMC1-9901M-B | Recombinant Mouse UIMC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
UIMC1 involved in several pathways and played different roles in them. We selected most pathways UIMC1 participated on our site, such as Cell Cycle,Cell Cycle Checkpoints,DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with UIMC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA Repair | COPS7B,YY1,RAD18,COPS3,NFRKB,INO80,KDM4B,RAD9,RTEL1,PPP4CA |
| HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) | EME2,RNF168,BRE,BABAM1,KIAA0146,TIPIN,EME1,RAD9,RNF4,TOPBP1 |
| DNA Double Strand Break Response | THRSP,CHEK2,RNF168,KDM4A,KDM4B,BRE,RAD50,EYA4,EYA3,EYA2 |
| G2/M DNA damage checkpoint | RNF168,BRCC3,FAM175A,BABAM1,TP53BP1,BRE,THRSP,BARD1 |
| G2/M Checkpoints | BABAM1,RAD9A,RAD1,THRSP,BARD1,RAD17,TP53BP1,RNF168,RAD9B,FAM175A |
| Cell Cycle Checkpoints | FAM175A,CDKN1B,CDK5RAP2,CDK2,RAD9,MCM8,CLSPN,BRE,RAD50,RAD1 |
| Cell cycle | CDKN1BB,NIPBL,BRE,CP110,BRCC3,CDK11B,MIS12,CEP164,SPC25,NDEL1 |
| DNA Double-Strand Break Repair | RAD9,DNA2,BABAM1,CHEK2,PARP2,TIMELESS,HUS1,RAD50,BARD1,TDP2 |
Protein Function
UIMC1 has several biochemical functions, for example, K63-linked polyubiquitin binding,histone binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UIMC1 itself. We selected most functions UIMC1 had, and list some proteins which have the same functions with UIMC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| histone binding | IPO7,SMARCA4A,HIST1H4B,HIST1H4H,MYSM1,PRKCBB,SIRT1,HIST2H3C,PIH1D1,HAT1 |
| K63-linked polyubiquitin binding | OTUD7B,SPRTN,ZRANB1B,SQSTM1,ZRANB1,RNF168,PRPF8,IKBKG,ATRIP,TAB2 |
| protein binding | FIP1L1,OSTA,HIST1H2AH,POLH,TRAF1,ARL4C,ARAP3,KLC4,C19orf47,SCN11A |
Interacting Protein
UIMC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UIMC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UIMC1.
FAM175A;BRCA1;PYCRL;CASK
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