UCK2
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Official Full Name
uridine-cytidine kinase 2 -
Overview
This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. -
Synonyms
UCK2;uridine-cytidine kinase 2;UMPK, uridine monophosphate kinase;uridine kinase;uridine monophosphokinase 2;cytidine monophosphokinase 2;uridine monophosphate kinase;testis-specific protein TSA903;UK;UMPK;TSA903;DKFZp686M04245
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- His
- T7
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
UCK2 involved in several pathways and played different roles in them. We selected most pathways UCK2 participated on our site, such as Pyrimidine metabolism,Drug metabolism - other enzymes,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UCK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CERS5,SMPD5,CYP26C1,BCAT2,ACY1,POC1BL,NDUFA7,POLR1B,NDUFA11,UROC1 |
| Drug metabolism - other enzymes | UGT1A4,TYMP,UGT1A6,UGT2A1,IMPDH1A,TPMT,IMPDH2,TK2,UGT2A3,UGT1AB |
| Pyrimidine metabolism | CMPK,CANT1A,POLR2J,NT5C2,POLE,RRM2B,CTPS1A,NT5C1BA,POLR2C,NME1 |
Protein Function
UCK2 has several biochemical functions, for example, ATP binding,nucleoside kinase activity,uridine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UCK2 itself. We selected most functions UCK2 had, and list some proteins which have the same functions with UCK2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| uridine kinase activity | UCK1,UCKL1,UCKL1A,UCK2A,UCK2B,CMPK1,UPRT |
| nucleoside kinase activity | UCK2A,UCK2B,TK1,UCK1,DCK,DGUOK |
| ATP binding | LIMK1A,DGKQ,DCLK1,GLULB,TYRO3,UBE2D1B,PHKG2,MCM3L,RIPK1,UBA1 |
Interacting Protein
UCK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UCK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UCK2.
TSC22D1;NEK6;VCAM1
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