UBAP1
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Official Full Name
ubiquitin associated protein 1 -
Overview
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
UBAP1;ubiquitin associated protein 1;UBAP, ubiquitin associated protein;ubiquitin-associated protein 1;MGC8710;NAG20;Nasopharyngeal carcinoma associated gene 20 protein;UAP;UBAP;nasopharyngeal carcinoma-associated gene 20 protein;UBAP-1
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- His
- His&T7
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
UBAP1 involved in several pathways and played different roles in them. We selected most pathways UBAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UBAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
UBAP1 has several biochemical functions, for example, protein binding,ubiquitin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBAP1 itself. We selected most functions UBAP1 had, and list some proteins which have the same functions with UBAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin binding | NPLOC4,UBE2N,CXCR4,TRP53INP2,USP16,SIRT2,USP25,RNF168,UCHL3,BRAP |
| protein binding | FLG,TAL2,RNF7,RPSA,PYGB,CLIC5,THRAP3,FAM54B,ZMAT4,CTLA4 |
Interacting Protein
UBAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBAP1.
PPIC;Map3k1;BQRF1
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References
- Collaud, S; Tischler, V; et al. Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN. BMC CANCER 15:-(2015).
- Ayyadevara, S; Balasubramaniam, M; et al. Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes. AGING CELL 14:35-48(2015).
