TXNDC3
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Official Full Name
thioredoxin domain containing 3 (spermatozoa) -
Overview
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6. -
Synonyms
TXNDC3;thioredoxin domain containing 3 (spermatozoa);thioredoxin domain-containing protein 3;CILD6;NME8;sperm specific thioredoxin 2;SPTRX2;NM23 H8;Spermatid specific thioredoxin 2;Sptrx 2;Thioredoxin domain containing protein 3;OTTHUMP00000128304;OTTHUMP00000207133;sperm-specific thioredoxin 2;spermatid-specific thioredoxin-2;NM23-H8;sptrx-2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TXNDC3-3500H | Recombinant Human TXNDC3, GST-tagged | E.coli | Human | GST | 7-370aa | |
| TXNDC3-623HCL | Recombinant Human TXNDC3 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
TXNDC3 involved in several pathways and played different roles in them. We selected most pathways TXNDC3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TXNDC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TXNDC3 has several biochemical functions, for example, microtubule binding,nucleoside diphosphate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TXNDC3 itself. We selected most functions TXNDC3 had, and list some proteins which have the same functions with TXNDC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule binding | MAP1B,ARHGEF2,KIFC3,KIF5A,LC3,KIF27,MAP205,CLIP3,EML2,MAPRE3B |
| nucleoside diphosphate kinase activity | NME5,NME2B.1,AK1,NME1,NME8,NME2,AK7,AK9,AK5,AK8 |
Interacting Protein
TXNDC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TXNDC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TXNDC3.
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