TUBA8
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Official Full Name
tubulin, alpha 8 -
Overview
This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families;(alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated;with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants. -
Synonyms
TUBA8;tubulin, alpha 8;TUBAL2;tubulin alpha-8 chain;Alpha tubulin 8;Alpha-tubulin 8;TBA8_HUMAN;Tubulin alpha 8 chain;Tubulin alpha chain like 2;Tubulin alpha chain-like 2
Recombinant Proteins
- Mouse
- Rat
- Chicken
- Human
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TUBA8-17614M | Recombinant Mouse TUBA8 Protein | Mammalian Cell | Mouse | His |
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| TUBA8-6360R | Recombinant Rat TUBA8 Protein | Mammalian Cell | Rat | His |
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| TUBA8-6994C | Recombinant Chicken TUBA8 | Mammalian Cell | Chicken | His |
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| TUBA8-655HCL | Recombinant Human TUBA8 293 Cell Lysate | HEK293 | Human | Non |
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| TUBA8-2192H | Recombinant Human TUBA8 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| TUBA8-6016R | Recombinant Rat TUBA8 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| TUBA8-6016R-B | Recombinant Rat TUBA8 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Tuba8-6727M | Recombinant Mouse Tuba8 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| TUBA8-9758M | Recombinant Mouse TUBA8 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TUBA8-9758M-B | Recombinant Mouse TUBA8 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TUBA8 involved in several pathways and played different roles in them. We selected most pathways TUBA8 participated on our site, such as Phagosome,Gap junction,Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phagosome | BMA1,Pla2r1,THBS3,COLEC12,ATP6V0CB,ATP6V0C,RAB5C,NCF1,SEC22BA,TLR4BA |
| Pathogenic Escherichia coli infection | CDH1,TUBA1C,YWHAZ,ABL1,ARPC5L,CD14,WAS,TUBB7P,TUBB2B,NCL |
| Gap junction | ITPR3,PRKACAA,TUBA3B,TUBA1L,MAPK1,MAPK3,GUCY1B3,TUBA3C,ADCY2B,TUBA1B |
Protein Function
TUBA8 has several biochemical functions, for example, GTP binding,GTPase activity,structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBA8 itself. We selected most functions TUBA8 had, and list some proteins which have the same functions with TUBA8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activity | RAB11B,DNM2,RABL2B,RHOT1,DNM1L,RAB5C,RAB28,RAB8A,RAB5AA,RAB27A |
| structural constituent of cytoskeleton | SPTB,ARPC3,KRT20,TUBGCP2,TUBE1,TLN2A,NEFL,INA,GFAP,TUBA1C |
| GTP binding | SAR1B,GUCY1A3,ARFRP1,RAB14,RHOUB,GIMAP8,RAB41,GNAO1,SAR1AB,GIMAP5 |
Interacting Protein
TUBA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBA8.
IKBKG;ARRB2;HTR7;SLC38A1
Resources
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References
- Tiriveedhi, V; Banan, B; et al. Role of defensins in the pathogenesis of chronic lung allograft rejection. HUMAN IMMUNOLOGY 75:370-377(2014).
- Dvorak, J; Sitorova, V; et al. Primary cilia in gastrointestinal stromal tumors. NEOPLASMA 61:305-308(2014).
