TUBA4A
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Official Full Name
tubulin, alpha 4a -
Overview
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. -
Synonyms
TUBA4A;tubulin, alpha 4a;TUBA1, tubulin, alpha 1 , tubulin, alpha 1 (testis specific);tubulin alpha-4A chain;FLJ30169;H2 ALPHA;tubulin H2-alpha;tubulin alpha-1 chain;tubulin, alpha 1 (testis specific);TUBA1;H2-ALPHA
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
- His&Myc
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TUBA4A-17613M | Recombinant Mouse TUBA4A Protein | Mammalian Cells | Mouse | His |
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| TUBA4A-6359R | Recombinant Rat TUBA4A Protein | Mammalian Cells | Rat | His |
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| TUBA4A-656HCL | Recombinant Human TUBA4A 293 Cell Lysate | HEK293 | Human | Non |
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| Tuba4a-342M | Recombinant Mouse Tuba4a protein, His&Myc-tagged | E.coli | Mouse | His&Myc | 1-448a.a. |
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| TUBA4A-6015R | Recombinant Rat TUBA4A Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| TUBA4A-6015R-B | Recombinant Rat TUBA4A Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| TUBA4A-9757M | Recombinant Mouse TUBA4A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TUBA4A-9757M-B | Recombinant Mouse TUBA4A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TUBA4A involved in several pathways and played different roles in them. We selected most pathways TUBA4A participated on our site, such as Phagosome,Gap junction,Pathogenic Escherichia coli infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBA4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gap junction | ITPR1,MAP2K2,RAF1B,CSNK1DB,PDGFD,MAPK7,DRD2B,HTR2CL1,GRM1,ITPR3 |
| Pathogenic Escherichia coli infection | TUBA1A,ROCK1,WASL,TUBB,TUBA1B,NCK2,OCLN,RHOA,TUBA8,TUBA3E |
| Phagosome | TLR4BB,FCGR1A,ATP6V1C2,H2-Q10,ATP6V0A2,TUBA1C,EEA1,BLA,ITGB5,TUBAL3 |
Protein Function
TUBA4A has several biochemical functions, for example, GTP binding,GTPase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBA4A itself. We selected most functions TUBA4A had, and list some proteins which have the same functions with TUBA4A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MAX,TTK,EXOC8,CAV1,PPIE,ARMCX1,CNPY2,FOXK2,FAM127B,GALR1 |
| structural constituent of cytoskeleton | TUBGCP3,GFAP,EPB42,ARPC3,TUBB1,KRT14,TUBA1L,TUBA8L2,BFSP2,NEFM |
| GTP binding | TUBG1,GIMAP2,RAC1,ARFRP1,RAC1B,RAB25B,ARHGAP5,NPR2,ERAS,ADSSL1 |
| GTPase activity | GNAI2,DIRAS3,GBP2,TUBA3D,GSPT2,RAB7L1,RAB5AA,RAB3D,RAB11BA,MFN1 |
Interacting Protein
TUBA4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBA4A here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBA4A.
CLIP1;EGFR;MYC;E2F1;SMAD2;SMAD1;STARD13;GNAI2;S100A8;ENO2;RPL12;TM4SF1;ACTN2
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