TTF2
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Official Full Name
transcription termination factor, RNA polymerase II -
Overview
This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. -
Synonyms
TTF2;transcription termination factor, RNA polymerase II;transcription termination factor 2;HuF2;F2;human factor 2;lodestar homolog;lodestar protein;transcription release factor 2;RNA polymerase II termination factor
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TTF2-3478H | Recombinant Human TTF2, GST-tagged | E.coli | Human | GST | 1-300aa | |
| TTF2-17583M | Recombinant Mouse TTF2 Protein | Mammalian Cells | Mouse | His |
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| TTF2-9733M | Recombinant Mouse TTF2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TTF2-9733M-B | Recombinant Mouse TTF2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TTF2 involved in several pathways and played different roles in them. We selected most pathways TTF2 participated on our site, such as Thyroid hormone synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TTF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Thyroid hormone synthesis | GPX8,ASGR2,ATP1B4,CANX,GNAQ,GPX7,CREB3L2,LRP2,TSHR,CREB3L3 |
Protein Function
TTF2 has several biochemical functions, for example, ATP binding,ATP-dependent helicase activity,DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TTF2 itself. We selected most functions TTF2 had, and list some proteins which have the same functions with TTF2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP-dependent helicase activity | DHX37,RECQL5,CHD6,CHD4A,BLM,ERCC6L2,SNRNP200,RTEL1,DHX36 |
| zinc ion binding | PPARG,TRIM35-34,S100A7,QPCT,PTER,Car12,SIRT5,KDM4B,C6AST4,VDRA |
| DNA-dependent ATPase activity | SMARCAL1,ERCC6,MSH4,XRCC2,CHD6,RAD51L1,CHD8,DDX11,RAD51D,MSH5 |
| ATP binding | GRK4,ABCF2A,GK5,NTRK2,P2RX4A,TNK1,RPS6KB1B,SKIV2L2,UBE2G1B,MYO3A |
| protein binding | PPP3CB,MRPS9,CORO1C,CTDNEP1,CEBPG,UCHL1,PTGES2,BASP1,ARHGEF38,NSMCE1 |
| DNA binding | HIST2H2AA4,POLM,ESR2B,DNA2,ZNF367,ZFP536,RPP21,FAM60AL,XRN1,HIST1H2BH |
Interacting Protein
TTF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TTF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TTF2.
CDC5L;SIRT3;SMAD7;NVL;MYBL2;SKIL;PRDX4;DRAP1;TNIP1;SMAD1;CDKL3;PDCD6IP;CLPB;DCP1A;TACC3;mdm2_human_probe
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