TSPAN8
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Official Full Name
tetraspanin 8 -
Overview
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. -
Synonyms
TSPAN8;tetraspanin 8;TM4SF3, transmembrane 4 superfamily member 3;tetraspanin-8;CO 029;anti TSPAN8;CO029;TM4SF3;Transmembrane 4 superfamily member 3;Tspan 8;Tumor associated antigen CO 029;tspan-8;OTTHUMP00000241500;OTTHUMP00000241501;OTTHUMP00000241502;tumor-associated antigen CO-029;CO-029
Recombinant Proteins
- Human
- Mouse
- Chicken
- Mus musculus
- Bovine
- Pongo Abelii
- Canine
- Cynomolgus
- E.coli
- N-hFc
- HEK293
- Mammalian Cells
- Human Cells
- His
- Non
- Fc&His
- mFc
- Avi&Fc&His
Involved Pathway
TSPAN8 involved in several pathways and played different roles in them. We selected most pathways TSPAN8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TSPAN8 has several biochemical functions, for example, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN8 itself. We selected most functions TSPAN8 had, and list some proteins which have the same functions with TSPAN8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| integrin binding | S1PR2,WISP1,VCAM1,ANXA7,CIB2,CD226,ADAM17,THBS1,PXN,CD151 |
Interacting Protein
TSPAN8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN8 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN8.
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References
