TSPAN2
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Official Full Name
tetraspanin 2 -
Overview
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. -
Synonyms
TSPAN2;tetraspanin 2;tetraspanin-2;FLJ12082;TSN2;TSPAN 2;6330415F13Rik;OTTHUMP00000013651;AW048009;B230119D02Rik;RP4-666F24.2;Tetraspan 2;Tetraspan TM4SF;Tetraspanin2;tetraspan NET-3;new EST tetraspan 3;tetraspanin 2 isoform;NET3;TSPAN-2
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mus musculus
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- Yeast
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TSPAN2-3457H | Recombinant Human TSPAN2, GST-tagged | E.coli | Human | GST | 101-199aa | |
| TSPAN2-2659Z | Recombinant Zebrafish TSPAN2 | Mammalian Cell | Zebrafish | His |
|
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| TSPAN2-6326R | Recombinant Rat TSPAN2 Protein | Mammalian Cell | Rat | His |
|
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| TSPAN2-708HCL | Recombinant Human TSPAN2 lysate | HEK293 | Human | Non |
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| RFL22311RF | Recombinant Full Length Rat Tetraspanin-2(Tspan2) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-221) |
|
| RFL23767HF | Recombinant Full Length Human Tetraspanin-2(Tspan2) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-221) |
|
| RFL29174MF | Recombinant Full Length Mouse Tetraspanin-2(Tspan2) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-221) |
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| TSPAN2-3628H | Recombinant Human TSPAN2 protein | E.coli | Human | Non | 112-188aa |
|
| TSPAN2-5541H | Recombinant Human TSPAN2 protein, His-tagged | Yeast | Human | His | 112-188aa |
|
| TSPAN2-5982R | Recombinant Rat TSPAN2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| TSPAN2-5982R-B | Recombinant Rat TSPAN2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
TSPAN2 involved in several pathways and played different roles in them. We selected most pathways TSPAN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TSPAN2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN2 itself. We selected most functions TSPAN2 had, and list some proteins which have the same functions with TSPAN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CCDC155,HIST1H4A,CTSK,NOL12,CD79B,IRAK2,KRTAP8-1,IGF2BP1,FAM128B,PRDX4 |
Interacting Protein
TSPAN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN2.
GRB2;PIK3R3;RABGAP1L;FOS
Resources
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References
- Johnson, EL; Chu, H; et al. Placental Hofbauer cells assemble and sequester HIV-1 in tetraspanin-positive compartments that are accessible to broadly neutralizing antibodies. Journal of the International AIDS Society 18:-(2015).
- Pagel, JM; Spurgeon, SE; et al. Otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, for relapsed or refractory NHL patients. BRITISH JOURNAL OF HAEMATOLOGY 168:38-45(2015).
