TSHB
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Official Full Name
thyroid stimulating hormone, beta -
Overview
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. -
Synonyms
TSHB;thyroid stimulating hormone, beta;TSH-B;TSH-BETA;thyrotropin subunit beta;thyrotropin beta chain;Thyrotropin subunit beta;Thyroid-stimulating hormone subunit beta;Thyrotropin beta chain;Thyrotropin alfa
Recombinant Proteins
- Human
- Rat
- Chicken
- Dog
- Mouse
- Zebrafish
- CHO
- HEK293
- E.coli
- Yeast
- Mammalian Cells
- Insect Cells
- Human Pituitary Gland
- Non
- Myc&DDK
- His
- His&GST
- His&Myc
- His&SUMO
- His&Fc&Avi
Involved Pathway
TSHB involved in several pathways and played different roles in them. We selected most pathways TSHB participated on our site, such as Neuroactive ligand-receptor interaction,Thyroid hormone synthesis,Regulation of lipolysis in adipocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with TSHB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ne thyroid disease | HLA-DQB1,HLA-C,HLA-DPA1,IFNA21,FAS,CD40LG,HLA-DOB,H2-AA,HLA-F,TPO |
| Regulation of lipolysis in adipocytes | PTGER3,LIPE,TSHR,PTGS1,PIK3CB,PRKG1,PIK3CA,PDE3B,PIK3CG,PNPLA2 |
| Thyroid hormone synthesis | GPX1,ITPR1,ATP1B3,ASGR2,Adcy4,PRKACB,TG,GPX7,TPO,FXYD2 |
| Neuroactive ligand-receptor interaction | GRIA4A,TAAR9,DRD1B,HTR1B,TACR3L,GRIA2A,PTH1RA,IL12,MC3R,LEPR |
| Autoi | Ifna15,HLA-DRB4,IFNA1,HLA-DQA2,HLA-G,FAS,CD40,HLA-C,HLA-DRB5,IFNA8 |
Protein Function
TSHB has several biochemical functions, for example, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TSHB itself. We selected most functions TSHB had, and list some proteins which have the same functions with TSHB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | SMTLA,FSD1,GALP,UTS2A,INHBB,THPO,INS1,PRL,INSL3,ADM2 |
Interacting Protein
TSHB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSHB here. Most of them are supplied by our site. Hope this information will be useful for your research of TSHB.
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