TRY
-
Official Full Name
trypsin -
Overview
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. -
Synonyms
TYR;tyrosinase (oculocutaneous albinism IA);OCA1A;OCAIA;SHEP3;Tyrosinase;EC 1.14.18.1;Monophenol monooxygenase;Tumor rejection antigen AB;SK29-AB;LB24-AB
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRY-690H |
Active Recombinant Human Tyrosinase (Oculocutaneous Albinism IA), His-tagged
|
E.coli | Human | His |
|
|
| TRY-9230Z | Recombinant Zebrafish TRY | Mammalian Cells | Zebrafish | His |
|
Involved Pathway
TRY involved in several pathways and played different roles in them. We selected most pathways TRY participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRY were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | PTGER1C,S1PR5A,LOC100328615,LPAR2,LHBETA1,GRIA1A,MTNR1A,MC4R,TAAR13D,MLNR |
Protein Function
TRY has several biochemical functions, for example, hydrolase activity,peptidase activity,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRY itself. We selected most functions TRY had, and list some proteins which have the same functions with TRY. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type peptidase activity | GZMB,PRSS41,PROCA,KLK1B11,TMPRSS2,DPP6,TMPRSS11G,KLK12,SLC38A8,GZMK |
| serine-type endopeptidase activity | PRSS59.1,PCSK5,RHBDL3,MCPT9,C2,PRSS58,HPR,AZU1,KLK1B22,F9A |
| peptidase activity | FOLH1,Casp3,METAP2A,REN,FAM49BA,DUB1,PM20D1,C1RA,PSMA6A,TMPRSS5 |
| hydrolase activity | GDPGP1,ACHE,UGT1A5,UNGA,ACP5B,STAMBPA,CTSLA,F9B,PSMB8F,ATAD1A |
Interacting Protein
TRY has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRY here. Most of them are supplied by our site. Hope this information will be useful for your research of TRY.
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