TRPV3
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Official Full Name
transient receptor potential cation channel, subfamily V, member 3 -
Overview
This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] -
Synonyms
TRPV3;transient receptor potential cation channel, subfamily V, member 3;OLMS;VRL3;transient receptor potential cation channel subfamily V member 3;VRL-3;vanilloid receptor-like 3;vanilloid receptor-related osmotically activated channel protein
Recombinant Proteins
- Human
- Mouse
- Mus musculus
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli expression system
- In vitro E. coli expression system
- His
- Non
- His&Flag
- His&Fc&Avi
Involved Pathway
TRPV3 involved in several pathways and played different roles in them. We selected most pathways TRPV3 participated on our site, such as Inflammatory mediator regulation of TRP channels,Ion channel transport,Stimuli-sensing channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPV3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Stimuli-sensing channels | TRPC4A,TTYH2,SLC9A10,ANO1,TRPM1A,CLIC2,TRDN,SLC17A3,TTYH3B,TRPC4 |
| TRP channels | TRPM1,TRPM6,TRPM4A,MCOLN3,TRPC5,MCOLN2,TRPM4C,TRPC4A,TRPM1A,TRPC5A |
| Ion channel transport | CLCN1,ANO7,CLCNKA,ATP1A1A.4,ATP1A1A.5,ATP13A,TRPC4A,CLCN6,TRPM1A,UNC79 |
| Inflammatory mediator regulation of TRP channels | MAPK8,BDKRB1,CALM1,GNAQ,ASIC4,PIK3CG,PLA2G6,PRKCB,PRKCD,Adcy4 |
| Transmembrane transport of small molecules | APOD,SLC24A4A,SCNN1D,MFSD7B,TRPC4APB,ADD3,FXYD7,RHAG,SLCO3A1,SLC4A8 |
Protein Function
TRPV3 has several biochemical functions, for example, calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPV3 itself. We selected most functions TRPV3 had, and list some proteins which have the same functions with TRPV3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium channel activity | CHRNA10,TRPC2,TRPV1,RYR1,PANX1,CACNA1SA,TRPC1,GRIN3A,PDE2A,TRPC5A |
Interacting Protein
TRPV3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPV3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPV3.
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