TRPM7
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Official Full Name
transient receptor potential cation channel, subfamily M, member 7 -
Overview
TRPs, mammalian homologs of the Drosophila transient receptor potential (TRP) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutant. -
Synonyms
TRPM7;transient receptor potential cation channel, subfamily M, member 7;transient receptor potential cation channel subfamily M member 7;CHAK1;LTRPC7;TRP PLIK;LTrpC-7;channel-kinase 1;LTRPC ion channel family member 7;long transient receptor pot
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Trpm7-344R | Recombinant Rat Trpm7 Protein, His-tagged | E.coli | Rat | His | Ile19~Gly179 | |
| TRPM7-3201Z | Recombinant Zebrafish TRPM7 | Mammalian Cells | Zebrafish | His |
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| TRPM7-4086C | Recombinant Chicken TRPM7 | Mammalian Cells | Chicken | His |
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| TRPM7-1169HFL | Recombinant Human TRPM7 protein, His&Flag-tagged | HEK293 | Human | Flag&His | 1-1865 aa |
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Involved Pathway
TRPM7 involved in several pathways and played different roles in them. We selected most pathways TRPM7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPM7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TRPM7 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TRPM7 itself. We selected most functions TRPM7 had, and list some proteins which have the same functions with TRPM7. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
TRPM7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPM7 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPM7.
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References
- Gilliam, JC; Wensel, TG; et al. TRP channel gene expression in the mouse retina. VISION RESEARCH 51:2440-2452(2011).
- Kim, TY; Shin, SK; et al. Identification of the phosphorylation sites on intact TRPM7 channels from mammalian cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 417:1030-1034(2012).
