TRMT5
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Official Full Name
TRM5 tRNA methyltransferase 5 homolog -
Overview
tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly;specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in;selected tRNAs using S-adenosyl methionine (Brule et al., 2004 (PubMed 15248782)). -
Synonyms
TRMT5;TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae);KIAA1393;tRNA (guanine(37)-N1)-methyltransferase;TRM5;M1G-methyltransferase;tRNA-N1G37 methyltransferase;tRNA [GM37] methyltransferase;tRNA methyltransferase 5 homolog;tRNA (guanine-N(1)
Recombinant Proteins
- Mouse
- Rhesus macaque
- Zebrafish
- Human
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRMT5-17422M | Recombinant Mouse TRMT5 Protein | Mammalian Cells | Mouse | His |
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| TRMT5-4983R | Recombinant Rhesus monkey TRMT5 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| TRMT5-7335Z | Recombinant Zebrafish TRMT5 | Mammalian Cells | Zebrafish | His |
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| TRMT5-753HCL | Recombinant Human TRMT5 293 Cell Lysate | HEK293 | Human | Non |
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| TRMT5-2804H | Recombinant Human TRMT5 Protein, His-tagged | E.coli | Human | His |
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| TRMT5-4797R | Recombinant Rhesus Macaque TRMT5 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| TRMT5-4797R-B | Recombinant Rhesus Macaque TRMT5 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| TRMT5-9640M | Recombinant Mouse TRMT5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TRMT5-9640M-B | Recombinant Mouse TRMT5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TRMT5 involved in several pathways and played different roles in them. We selected most pathways TRMT5 participated on our site, such as Gene Expression,Synthesis of wybutosine at G37 of tRNA(Phe),tRNA modification in the nucleus and cytosol, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRMT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| tRNA modification in the nucleus and cytosol | ALKBH8,CDKAL1,TYW5,THG1L,QTRT1,NSUN2,TRDMT1,ADAT3,LAGE3,PUS1 |
| Synthesis of wybutosine at G37 of tRNA(Phe) | TYW5,TYW1,LCMT2,TRMT12,TYW3 |
| Gene Expression | CCDC76,PAIP1,TRDMT1,GATAD2A,ZNF215,ZNF785,ZIK1,VDRB,ZNF529,SCO1 |
| tRNA processing | ALKBH8,RPP14,LBH,ADAT3,POP1,RPP30,TSEN15,TYW1,ZBTB8OS,TSEN54 |
Protein Function
TRMT5 has several biochemical functions, for example, tRNA (guanine(37)-N(1))-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRMT5 itself. We selected most functions TRMT5 had, and list some proteins which have the same functions with TRMT5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
TRMT5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRMT5 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRMT5.
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