TRIP6
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Official Full Name
thyroid hormone receptor interactor 6 -
Overview
This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. -
Synonyms
TRIP6;thyroid hormone receptor interactor 6;thyroid receptor-interacting protein 6;MGC3837;MGC4423;MGC10556;MGC10558;MGC29959;OIP1;ZRP 1;OIP-1;OPA interacting protein 1;OPA-interacting protein 1;Thyroid receptor interacting protein 6;TR-interacting protein 6;TRI6;TRIP 6;TRIP-6;TRIP6_HUMAN;ZRP-1;ZRP1;Zyxin related protein 1;Zyxin-related protein 1;OTTHUMP00000211326;thyroid hormone receptor interacting protein 6;TRIP6i2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRIP6-3424H | Recombinant Human TRIP6, His-tagged | E.coli | Human | His | C-350aa | |
| TRIP6-638H | Recombinant Human TRIP6 Protein, His/GST-tagged | E.coli | Human | His&GST | Cys279~Cys476 | |
| Trip6-639M | Recombinant Mouse Trip6 Protein, His/GST-tagged | E.coli | Mouse | His&GST | Gly281~Glu471 | |
| TRIP6-608H | Recombinant Human TRIP6 Protein, GST-His-tagged | E.coli | Human | His&GST |
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| TRIP6-758HCL | Recombinant Human TRIP6 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
TRIP6 involved in several pathways and played different roles in them. We selected most pathways TRIP6 participated on our site, such as NOD-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| NOD-like receptor signaling pathway | IL18,TAB3,CCL2,SUGT1,MAPK12A,PSTPIP1A,HSP90AA1,MAPK12B,IL1B,IL8L2 |
Protein Function
TRIP6 has several biochemical functions, for example, interleukin-1 receptor binding,kinase binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIP6 itself. We selected most functions TRIP6 had, and list some proteins which have the same functions with TRIP6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | THEMIS,THRB,C5orf13,LCE3E,BLOC1S6,RHNO1,C3,AIM2,CAB39L,VPS4A |
| thyroid hormone receptor binding | TAF7,MED24,NR0B2,HMGN3,MED17,GTF2B,TRIP12,THRAP3,MED4,NUP62 |
| zinc ion binding | KMT2E,RNF34A,ADH8A,RXRAA,USP20,YY1,THRA,LNX2,PGLYRP6,RNF40 |
| interleukin-1 receptor binding | IL1RAP,IL36B,IL37,IL36G,TLR5,IL1F10,IRAK4,Il1f6,IL36A,IL1A |
| poly(A) RNA binding | FLNA,HOXB6,SF3B14,PEG10,MANF,TPR,ZFC3H1,RPS15A,POLDIP3,POLR2A |
| kinase binding | HPCA,C2orf44,LDHB,DLG1,RPS3,WWC3,SP100,BCL10,PRDX3,JAKMIP3 |
Interacting Protein
TRIP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIP6.
HOXA9;NCK2;AQP1;BYSL;EXOC3-AS1
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