TRIM56
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Official Full Name
tripartite motif containing 56 -
Synonyms
TRIM56;tripartite motif containing 56;E3 ubiquitin-protein ligase TRIM56;RNF109;DKFZp667O116;A130009K11Rik;FLJ35608;Gm452;MGC37358;OTTMUSP00000027392;RING finger protein 109;Tripartite motif containing protein 56;OTTHUMP00000211343;tripartite motif-containing 56;tripartite motif-containing protein 56
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRIM56-2992H | Recombinant Human TRIM56 protein, His-tagged | E.coli | Human | His | 1-258 aa | |
| TRIM56-17383M | Recombinant Mouse TRIM56 Protein | Mammalian Cells | Mouse | His |
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| TRIM56-767HCL | Recombinant Human TRIM56 293 Cell Lysate | HEK293 | Human | Non |
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| TRIM56-9614M | Recombinant Mouse TRIM56 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TRIM56-9614M-B | Recombinant Mouse TRIM56 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TRIM56 involved in several pathways and played different roles in them. We selected most pathways TRIM56 participated on our site, such as Cytosolic sensors of pathogen-associated DNA,Immune System,Innate Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM56 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | ACTR1A,GRAP2B,NCKAP1,IRF9,CASPB,Txn1,ACTR2B,EDARADD,WIPF3,RNF41 |
| Innate Immune System | IFI16,FCN1,TXNIP,TANK,IRF2,CLEC5A,CFHL3,LAT2,RNF216,DEFB103A |
| Regulation of innate immune responses to cytosolic DNA | NLRP4C,TREX1,NLRP4E,NLRP4B,DDX41,NLRP4 |
| Cytosolic sensors of pathogen-associated DNA | POLR3GLA,POLR3G,AGER,POLR3F,APPA,CRCP,MB21D1,S100A12,TICAM1,CHST13 |
Protein Function
TRIM56 has several biochemical functions, for example, ligase activity,poly(A) RNA binding,ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM56 itself. We selected most functions TRIM56 had, and list some proteins which have the same functions with TRIM56. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | MARCH10,HERC3,TRIM13,TRIM22,RNF34,NHLRC1,TRIM58,TTLL9,ACSL1,RNF182 |
| poly(A) RNA binding | SNRPN,HNRNPDL,S100A4,RBMX2,RPUSD4,RPL10,RPS13,FAM98C,HNRNPUL1,RPL36 |
| zinc ion binding | ADAM8A,HERC2,SETDB1,RBX1,ZBBX,MEP1A.1,QPCTL,PCGF3,TRIM72,RABGEF1 |
| ubiquitin-protein transferase activity | UBE2D2A,G2E3,TRIM32,TRIM13,CDC34,TOPORS,RC3H2,ITCHA,MUL1,UBE2D4 |
Interacting Protein
TRIM56 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM56 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM56.
b4dyc6_human;HSP90AA1;HSP90AB1;CNBP;FKBP5;PTGES3;HSP90AB1;UBE2H;yapG;Npro;d2cfj1_9flav;Ccdc9;ssrna_cg;MYH9;Espl1;q5u8y3_9flav;USP43;Fam60a;SPC24;Cep72
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References
- Liu, BM; Li, NL; et al. Overlapping and Distinct Molecular Determinants Dictating the Antiviral Activities of TRIM56 against Flaviviruses and Coronavirus. JOURNAL OF VIROLOGY 88:13821-13835(2014).
- Cui, ZB; Cao, W; et al. TRIM24 Overexpression Is Common in Locally Advanced Head and Neck Squamous Cell Carcinoma and Correlates with Aggressive Malignant Phenotypes. PLOS ONE 8:-(2013).
