TRIM39

  • Official Full Name

    tripartite motif containing 39

  • Overview

    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms.

  • Synonyms

    TRIM39;tripartite motif containing 39;ring finger protein 23 , RNF23, tripartite motif containing 39;tripartite motif-containing protein 39;HGNC:10065;MGC32984;Ring finger protein 23;RNF23;Testis abundant finger protein;TFP;TFP RING FINGER PROTEIN 23;testis-abundant finger protein;tripartite motif-containing 39;TRIM39B
Cat.# Product name Source (Host) Species Tag Protein Length Price
TRIM39-1345C Recombinant Chicken TRIM39 Mammalian Cells Chicken His
TRIM39-6277R Recombinant Rat TRIM39 Protein Mammalian Cells Rat His
TRIM39-778HCL Recombinant Human TRIM39 293 Cell Lysate HEK293 Human Non
TRIM39-5934R Recombinant Rat TRIM39 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
TRIM39-5934R-B Recombinant Rat TRIM39 Protein Pre-coupled Magnetic Beads HEK293 Rat
Trim39-6655M Recombinant Mouse Trim39 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK

    Involved Pathway

    TRIM39 involved in several pathways and played different roles in them. We selected most pathways TRIM39 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM39 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System KIF4A,BLMH,VPRBP,CD300A,SPSB2,CTSL1,EVL,CLEC2D,LILRB5,SPSB1
    Immune System CD160,CTLA4,ARIH1L,HECTD3,NCR3LG1,RCA2.1,IFIT12,NCKAP1,GHRB,KIF20A
    presentation SEC23A,UBE2V2,RNF41,TRAF7,SPSB4,DTX3L,B2ML,RNF34,RNF144B,STUB1
    Antigen processing: Ubiquitination &amp RNF41,UBE2E3,UBA5,RNF14,DZIP3,RNF144B,DTX3L,PJA2,MKRN1,ASB2
    Class I MHC mediated antigen processing &amp TPP2,KLHL20,RNF19B,UBE2U,ASB2,TRIM9,ASB7,RNF6,RNF138,ERAP1
    Proteasome degradation UBE2L6,RNF41,SH3RF1,HECTD3,WWP1,ASB17,TRIM41,TRIM9,DZIP3,RNF4

    Protein Function

    TRIM39 has several biochemical functions, for example, identical protein binding,ligase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM39 itself. We selected most functions TRIM39 had, and list some proteins which have the same functions with TRIM39. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding PHF11,UQCRC2,EHMT1B,SP140L,ZNF346,HIF1AN,PHF1,SNAI1A,TTF2,TAB2
    ligase activity RNF5,RNF14,NSMCE2,NHLRC1,RANBP2,ATG10,TRIM68,HLTF,TRIM23,TTC3
    identical protein binding CEACAM5,LYZ2,PTEN,YWHAZ,TP73,SH2B2,CEP72,CEP57L1,SERPINB1A,RIPK3
    protein binding COL8A1,TSSK4,ABCD1,USP25,HSPA8,CENPJ,AMELX,CA8,CLEC4G,CHEK1

    Interacting Protein

    TRIM39 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM39 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM39.

    UBE2D1;TRIM17;UBE2D3

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