TRIM27

  • Official Full Name

    Tripartite Motif Containing 27

  • Overview

    This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a;RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It;interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in;the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the;RET gene product has been shown to result in production of the ret transforming protein.

  • Synonyms

    TRIM27;tripartite motif containing 27;RFP;RNF76;zinc finger protein RFP;OTTHUMP00000029314;OTTHUMP00000107284;ret finger protein;RING finger protein 76;RFP transforming protein;tripartite motif-containing 27;tripartite motif protein TRIM27;tripartite motif-containing protein 27

Recombinant Proteins

  • Mouse
  • Chicken
  • Rhesus macaque
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
TRIM27-17352M Recombinant Mouse TRIM27 Protein Mammalian Cells Mouse His
TRIM27-2375C Recombinant Chicken TRIM27 Mammalian Cells Chicken His
TRIM27-3719C Recombinant Chicken TRIM27 Mammalian Cells Chicken His
TRIM27-4959R Recombinant Rhesus monkey TRIM27 Protein, His-tagged Mammalian Cells Rhesus macaque His
TRIM27-687H Recombinant Human TRIM27 Protein, His-tagged E.coli Human His
TRIM27-786HCL Recombinant Human TRIM27 293 Cell Lysate HEK293 Human Non
TRIM27-4773R Recombinant Rhesus Macaque TRIM27 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
TRIM27-4773R-B Recombinant Rhesus Macaque TRIM27 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
TRIM27-9599M Recombinant Mouse TRIM27 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
TRIM27-9599M-B Recombinant Mouse TRIM27 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    TRIM27 involved in several pathways and played different roles in them. We selected most pathways TRIM27 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    TRIM27 has several biochemical functions, for example, DNA binding,ligase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM27 itself. We selected most functions TRIM27 had, and list some proteins which have the same functions with TRIM27. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding FBP1,CYP46A1.4,ELP3,GIT2B,SHRPRBCK1R,ACAN,ZNF221,AOX4,ZNF302,PPM1AA
    zinc ion binding TK1,PHC2,TCF19,MIB1,ZDHHC15,BTR12,PCGF2,NR1D2,RNF217,TRIM61
    ligase activity SYVN1,MUL1,RNF135,SH3RF1,PJA1,SHPRH,UBE3C,TRIM11,RING1,E4F1
    transmembrane receptor protein tyrosine kinase activity NTRK3A,FLT1,ERBB2,EPHB4A,ROS1,KITB,CADM2B,TEK,RET,IGF1RB
    nucleic acid binding TDRKH,GFI1AA,RNASEL3,GLIS2,EWSR1A,ZBTB2B,WBP4,DHX37,AGO3B,ENPP1
    protein binding TP53RK,BOLA1,RYR1B,COMP,UVRAG,GOLSYN,TMED2,FAM110C,UQCC1,VPS41
    ubiquitin-protein transferase activity MIB1,MGRN1,UBA1,NSMCE1,TRIM21,TRIM62,MARCH5L,ITCHA,TRAF4A,PRP19
    DNA binding NR2F5,ZBTB41,NR1D2B,POU3F1,POGZ,HIST2H2BE,EMX3,OTX1A,PDS5B,HOXB2A

    Interacting Protein

    TRIM27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM27 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM27.

    NEDD9;JOSD1;PPP1R18;ZNF417;TUFT1

    Resources

    References

    • Oh, Y; Chung, KC; et al. UHRF2, a Ubiquitin E3 Ligase, Acts as a Small Ubiquitin-like Modifier E3 Ligase for Zinc Finger Protein 131. JOURNAL OF BIOLOGICAL CHEMISTRY 288:9102-9111(2013).
    • Horio, M; Kato, T; et al. Expression of RET finger protein predicts chemoresistance in epithelial ovarian cancer. CANCER MEDICINE 1:218-229(2012).

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All TRIM27 Products

    Required fields are marked with *

    My Review for All TRIM27 Products

    Required fields are marked with *