TRIM16
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Official Full Name
tripartite motif containing 16 -
Overview
This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. -
Synonyms
TRIM16;tripartite motif containing 16;tripartite motif-containing protein 16;EBBP;estrogen responsive B box protein;tripartite motif-containing 16;estrogen-responsive B box protein;DKFZp434O1826
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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TRIM16-1822HCL | Recombinant Human TRIM16 cell lysate | Human | Non |
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TRIM16-0414H | Recombinant Human TRIM16 Protein (A2-P564), Tag Free | Insect Cells | Human | Non | A2-P564 |
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TRIM16-0415H | Recombinant Human TRIM16 Protein (A2-P564), His/Strep tagged | Insect Cells | Human | His&Strep | A2-P564 |
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Involved Pathway
TRIM16 involved in several pathways and played different roles in them. We selected most pathways TRIM16 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
TRIM16 has several biochemical functions, for example, DNA binding,NACHT domain binding,interleukin-1 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM16 itself. We selected most functions TRIM16 had, and list some proteins which have the same functions with TRIM16. You can find most of the proteins on our site.
Function | Related Protein |
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NACHT domain binding | CARD8 |
zinc ion binding | PDLIM5B,SYTL4,ZCCHC12,RNF40,DNMT5,MIB2,SMAD3,MEP1A.1,LNPEP,ZCWPW2 |
interleukin-1 binding | HAX1,A2M |
protein binding | EFEMP1,MEF2A,SIL1,UBA52,P4HA3,ARHGEF4,HIST1H2AI,MSMB,LPA,HNF4A |
DNA binding | ZNF84,HMBOX1,RAG2,ENG1A,YBX2,ZFP574,PCBP4,NFIXB,FOXA,BRIP1 |
Interacting Protein
TRIM16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM16 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM16.
TINF2;VIM;E2F1;TERF1;SETDB1;ACD;POT1;Sidt2;Gnpnat1;Rhoa
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References
- Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
- Evans, ME; Kumkhaek, C; et al. TRIM5 alpha Variations Influence Transduction Efficiency With Lentiviral Vectors in Both Human and Rhesus CD34+Cells In Vitro and In Vivo. MOLECULAR THERAPY 22:348-358(2014).