Creative BioMart to Present at BPS 2025 Annual Meeting | February 15-19, 2025 Learn More

TRIM16

Official Full Name

tripartite motif containing 16
Overview

This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined.
Synonyms

TRIM16; tripartite motif containing 16; tripartite motif-containing protein 16; EBBP; estrogen responsive B box protein; tripartite motif-containing 16; estrogen-responsive B box protein; DKFZp434O1826;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TRIM16-1822HCL	Recombinant Human TRIM16 cell lysate		Non		Inquiry
Human	TRIM16-0414H	Recombinant Human TRIM16 Protein (A2-P564), Tag Free	Insect Cell	Non	A2-P564	Inquiry
Human	TRIM16-0415H	Recombinant Human TRIM16 Protein (A2-P564), His/Strep tagged	Insect Cell	His&Strep	A2-P564	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

TRIM16 involved in several pathways and played different roles in them. We selected most pathways TRIM16 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TRIM16 has several biochemical functions, for example, DNA binding, NACHT domain binding, interleukin-1 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM16 itself. We selected most functions TRIM16 had, and list some proteins which have the same functions with TRIM16. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	EZH2;FOSB;RAD51B;FOXO1B;NUSAP1;CASZ1;ATOH7;RAD51C;SMC1B
NACHT domain binding	CARD8;TRIM16
interleukin-1 binding	A2M;TRIM16;HAX1
protein binding	CAND2;LMO4;XRCC3;LHX4;CCDC42;FAS;CHMP5;TUBA3E;TMUB2
zinc ion binding	MARCH1;PDLIM2;SIRT3;MARCH10;RFPL2;ADH1;BRPF3;RNF34;SLC30A8

TRIM16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM16 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM16.

TINF2; VIM; E2F1; TERF1; SETDB1; ACD; POT1; Sidt2; Gnpnat1; Rhoa

Research Area

Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).

Evans, ME; Kumkhaek, C; et al. TRIM5 alpha Variations Influence Transduction Efficiency With Lentiviral Vectors in Both Human and Rhesus CD34+Cells In Vitro and In Vivo. MOLECULAR THERAPY 22:348-358(2014).