TRAT1
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Official Full Name
T cell receptor associated transmembrane adaptor 1 -
Overview
Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells. -
Synonyms
TRAT1;T cell receptor associated transmembrane adaptor 1;TRIM;TCRIM;HSPC062;T-cell receptor-associated transmembrane adapter 1;pp29/30;T cell receptor interacting molecule;T-cell receptor interacting molecule;T-cell receptor-interacting molecule
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRAT1-3398H | Recombinant Human TRAT1, His-tagged | E.coli | Human | His | 30-186aa | |
| TRAT1-17314M | Recombinant Mouse TRAT1 Protein | Mammalian Cell | Mouse | His |
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| TRAT1-492H | Recombinant Human TRAT1 Protein, His-tagged | E.coli | Human | His |
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| TRAT1-701HCL | Recombinant Human TRAT1 lysate | HEK293 | Human | Non |
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| TR1-2630H | Recombinant Human TRat 1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Trat1-6634M | Recombinant Mouse Trat1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| TRAT1-9574M | Recombinant Mouse TRAT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| TRAT1-9574M-B | Recombinant Mouse TRAT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| TRAT1-958H | Recombinant Human TRAT1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
TRAT1 involved in several pathways and played different roles in them. We selected most pathways TRAT1 participated on our site, such as Adaptive Immune System,Constitutive Signaling by Aberrant PI3K in Cancer,DAP12 interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | UBR1,STIM1B,LRRC41,ACTR1B,UBE2F,AP2S1,KIF20A,AKR1C1,PJA2,FGF20A |
| Constitutive Signaling by Aberrant PI3K in Cancer | FRS2,HBEGF,NRG4,NRG3,EGF,KLB |
| Disease | FKBP1A,WHSC2,AP2A2,CDK9,NUP35,DPF1,APOBEC3G,FDXR,TAF1L,OS9 |
| Diseases of signal transduction | CDK8,CPSF6,KREMEN2,RBP1,CTBP2,HDAC5,RBP4,JAG1,MYO18A,RLBP1 |
| DAP12 signaling | NRG2A,PRKAR1AA,WDR83,AGO3,FGF8B,PAQR3B,MARK3,FRS2,DUSP5,FGF18B |
| Downstream TCR signaling | UBE2V1,HLA-DQB2 |
| DAP12 interactions | MOV10,PEA15A,DUSP5,AGO1,SPRED3,FRS2B,TREM1,SIRPB1,LCP2A,SIGLEC15 |
| Downstream signal transduction | SPNA1,FGF10B,DUSP9,PEBP1,RASGEF1A,CRKL,FGFR1B,RASGRP4,MOV10,WDR83 |
Protein Function
TRAT1 has several biochemical functions, for example, transmembrane receptor protein tyrosine kinase adaptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAT1 itself. We selected most functions TRAT1 had, and list some proteins which have the same functions with TRAT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane receptor protein tyrosine kinase adaptor activity | GAB2,PIK3R1,IRS1,SH2B2,FRS2,BLNK,STAP1,SHC1,DOK2 |
Interacting Protein
TRAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAT1.
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