TRAT1

  • Official Full Name

    T cell receptor associated transmembrane adaptor 1

  • Overview

    Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.

  • Synonyms

    TRAT1;T cell receptor associated transmembrane adaptor 1;TRIM;TCRIM;HSPC062;T-cell receptor-associated transmembrane adapter 1;pp29/30;T cell receptor interacting molecule;T-cell receptor interacting molecule;T-cell receptor-interacting molecule

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
TRAT1-3398H Recombinant Human TRAT1, His-tagged E.coli Human His 30-186aa
TRAT1-17314M Recombinant Mouse TRAT1 Protein Mammalian Cells Mouse His
TRAT1-492H Recombinant Human TRAT1 Protein, His-tagged E.coli Human His
TRAT1-701HCL Recombinant Human TRAT1 lysate HEK293 Human Non
TR1-2630H Recombinant Human TRat 1 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
Trat1-6634M Recombinant Mouse Trat1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
TRAT1-9574M Recombinant Mouse TRAT1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
TRAT1-9574M-B Recombinant Mouse TRAT1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
TRAT1-958H Recombinant Human TRAT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc

    Involved Pathway

    TRAT1 involved in several pathways and played different roles in them. We selected most pathways TRAT1 participated on our site, such as Adaptive Immune System,Constitutive Signaling by Aberrant PI3K in Cancer,DAP12 interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Constitutive Signaling by Aberrant PI3K in Cancer HBEGF,FRS2,EGF,NRG3,KLB,NRG4
    Diseases of signal transduction TRIM24,DERL2,OPN1MW2,HEY2,MIB1,KREMEN2,OPN1SW,OPN1LW,OS9,CTBP1
    DAP12 signaling PAQR3A,PRKAR1AA,DAB2IPB,GRAP2A,NEFLB,AGO2,SPTA1,LCP2A,PTPRA,PEA15A
    Disease WHSC2,CPSF4,TCEA1,TCEB3,TICAM1,TLR6,FDX1L,AP2S1,GCKR,TH1L
    Adaptive Immune System ASB9,KIF3C,IGHM,CD96,ICAM4,RASGRP2,CXADR,UBE2J2,ERAP1,CMTM2A
    DAP12 interactions NEFLB,IL17RD,SPTA1,DUSP9,TREM1,AHCYL1,DUSP5,SPTBN2,LAMTOR2,KBTBD7
    Downstream signal transduction DUSP10,SPTBN1,JAK1,PAQR3A,AGO2,FGF10B,DUSP2,AGO1,IL17RD,PEA15A
    Downstream TCR signaling HLA-DQB2,UBE2V1

    Protein Function

    TRAT1 has several biochemical functions, for example, transmembrane receptor protein tyrosine kinase adaptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAT1 itself. We selected most functions TRAT1 had, and list some proteins which have the same functions with TRAT1. You can find most of the proteins on our site.

    Function Related Protein
    transmembrane receptor protein tyrosine kinase adaptor activity GAB2,IRS1,SHC1,SH2B2,PIK3R1,BLNK,DOK2,FRS2,STAP1

    Interacting Protein

    TRAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAT1.

    Resources

    Research Area

    T Cell Antigen Recognition

    References

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