TRAIP
-
Official Full Name
TRAF interacting protein -
Overview
This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. -
Synonyms
TRAIP;TRAF interacting protein;TRAF-interacting protein;ring finger protein 206;RNF206;TRIP
Recombinant Proteins
- Zebrafish
- Mouse
- Chicken
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- N-10xHis
- N-6xHis
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRAIP-11644Z | Recombinant Zebrafish TRAIP | Mammalian Cells | Zebrafish | His |
|
|
| TRAIP-17294M | Recombinant Mouse TRAIP Protein | Mammalian Cells | Mouse | His |
|
|
| TRAIP-2299C | Recombinant Chicken TRAIP | Mammalian Cells | Chicken | His |
|
|
| TRAIP-31614TH | Recombinant Human TRAIP | E.coli | Human | Non | Full L. |
|
| TRAIP-814HCL | Recombinant Human TRAIP 293 Cell Lysate | HEK293 | Human | Non |
|
|
| TRAIP-4814H | Recombinant Human TRAIP protein, 10xHis-tagged | E.coli | Human | N-10xHis | 1-469aa |
|
| TRAIP-4815H | Recombinant Human TRAIP protein, 6xHis-tagged | E.coli | Human | N-6xHis | 1-469aa |
|
| TRAIP-9562M | Recombinant Mouse TRAIP Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| TRAIP-9562M-B | Recombinant Mouse TRAIP Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
TRAIP involved in several pathways and played different roles in them. We selected most pathways TRAIP participated on our site, such as TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAIP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TNF-alpha/NF-kB Signaling Pathway | DAP,TANK,LRPPRC,UNC5CL,RNF216,COPS3,CSNK2A1P,KTN1,SMARCE1,G3BP2 |
Protein Function
TRAIP has several biochemical functions, for example, ligase activity,protein binding,receptor signaling protein activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAIP itself. We selected most functions TRAIP had, and list some proteins which have the same functions with TRAIP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | RNF130,BIRC3,RNF217,TRAF7,GATB,TRIM39,RNF20,ATG3,TRIM33,C12orf51 |
| receptor signaling protein activity | NCR1,SMAD1,FCAR,CD3E,TGFBR1,PDCL,RGS12B,cgr2b,ARAF,DOK5 |
| ubiquitin protein ligase activity | HECTD3,UBE2V1,AKTIP,FBXW11,FBXO40,PPIL2,RNF181,RNF2,HLTF,ZNRF2 |
| zinc ion binding | RNF41,KDM5BA,CA15B,LHX1B,PCGF1,TADA2B,ZNF34,ZNF330,MEP1B,TRIM35-21 |
| protein binding | PPM1A,PRPSAP1,PHAX,TATDN1,ZNF550,LARP2,SPATA7,MAMSTR,NRIP2,GRIFIN |
Interacting Protein
TRAIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAIP here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAIP.
MAPRE2;FYN;NCK1;PLCG1;GRB2;HIP2;UBOX5;TRIM23;UBE2H;RNF4;UBE2U;TRIM41;TSG101;UBE2Z;RNF114
Resources
Related Services
Related Products
References
- Hostager, BS; Kashiwada, M; et al. HOIL-1L Interacting Protein (HOIP) Is Essential for CD40 Signaling. PLOS ONE 6:-(2011).
- Hostager, BS; Fox, DK; et al. HOIL-1L Interacting Protein (HOIP) as an NF-kappa B Regulating Component of the CD40 Signaling Complex. PLOS ONE 5:-(2010).
