TPD52L2
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Official Full Name
tumor protein D52-like 2 -
Overview
This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. -
Synonyms
TPD52L2;tumor protein D52-like 2;tumor protein D54;D54;hD54;TPD54;2810411G23Rik;AU016537;C86069;DKFZp686A1765;MGC73020;RP23 33L3.2;TPD54_HUMAN;tumor protein D52 like 2;OTTHUMP00000031612;OTTHUMP00000031613;OTTHUMP00000031614;OTTHUMP00000031615;OTTHUMP00000031616;OTTHUMP00000031617;HCCR-binding protein 2
Recombinant Proteins
- Chicken
- Rat
- Human
- Mouse
- Mammalian Cells
- HEK293
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TPD52L2-2552C | Recombinant Chicken TPD52L2 | Mammalian Cells | Chicken | His |
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| TPD52L2-6237R | Recombinant Rat TPD52L2 Protein | Mammalian Cells | Rat | His |
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| TPD52L2-1814HCL | Recombinant Human TPD52L2 cell lysate | Human | Non |
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| TPD52L2-2437H | Recombinant Human TPD52L2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| TPD52L2-5894R | Recombinant Rat TPD52L2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| TPD52L2-5894R-B | Recombinant Rat TPD52L2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Tpd52l2-6593M | Recombinant Mouse Tpd52l2 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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Involved Pathway
TPD52L2 involved in several pathways and played different roles in them. We selected most pathways TPD52L2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TPD52L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
TPD52L2 has several biochemical functions, for example, poly(A) RNA binding,protein binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TPD52L2 itself. We selected most functions TPD52L2 had, and list some proteins which have the same functions with TPD52L2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | TNNC1,TRIM37,CADM1,FZD9,PVRL3B,BOK,CRYBA1,NOS1,SNX9,FAM109A |
| protein heterodimerization activity | HIST1H3F,SOX15,TGFB3,IKZF4,NEUROD2,MAFGA,RALGAPA1,SYCP2,JAM2,CHRNA5 |
| poly(A) RNA binding | PURG,GSPT2,MRPL13,CCDC108,COA6,ARF1,TAF15,SEC23IP,ALG13,CPNE3 |
| protein binding | MBL2,SVIL,TNNI3K,C1orf109,POT1,LRRC47,ZNF511,CRP,UBQLN4,CRELD2 |
Interacting Protein
TPD52L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPD52L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TPD52L2.
IKBKE;APP;ADORA2B;mtaD;q8d1p4_yerpe;1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate
Resources
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References
- He, YC; Chen, FS; et al. Knockdown of tumor protein D52-like 2 induces cell growth inhibition and apoptosis in oral squamous cell carcinoma. CELL BIOLOGY INTERNATIONAL 39:264-271(2015).
- Yang, M; Wang, XY; et al. Tumor Protein D52-Like 2 Contributes to Proliferation of Breast Cancer Cells. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 30:1-7(2015).
