TPCN1
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Official Full Name
two pore segment channel 1 -
Synonyms
TPCN1;two pore segment channel 1;18182;ENSG00000186815;TPC1;12q24.13;FLJ20612, KIAA1169;two pore calcium channel protein 1;two pore calcium channel protein 1;two-pore channel 1;two-pore segment channel 1;voltage-dependent calcium channel protein TPC1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TPCN1-17247M | Recombinant Mouse TPCN1 Protein | Mammalian Cells | Mouse | His |
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| TPCN1-6236R | Recombinant Rat TPCN1 Protein | Mammalian Cells | Rat | His |
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| TPCN1-5893R | Recombinant Rat TPCN1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| TPCN1-5893R-B | Recombinant Rat TPCN1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| TPCN1-9529M | Recombinant Mouse TPCN1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| TPCN1-9529M-B | Recombinant Mouse TPCN1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TPCN1 involved in several pathways and played different roles in them. We selected most pathways TPCN1 participated on our site, such as Ion channel transport,Stimuli-sensing channels,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with TPCN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | SLC12A5B,ATP2B1B,TRPC4,AQP8A.1,SLCO3A1,TRPC4A,NIPA1,SLC9A5,ABCE1,SLC20A1A |
| Ion channel transport | TRPM1A,HTR3C,TRPM4A,CLCN7,BEST1,ASIC1A,BSND,BEST3,ATP13A5,CLCN4-2 |
| Stimuli-sensing channels | TTYH3,CLIC2,TTYH2,ANO1,OSTM1,ANO6,SLC9A10,ANO5B,TRPA1B,FKBP1B |
Protein Function
TPCN1 has several biochemical functions, for example, NAADP-sensitive calcium-release channel activity,calcium channel activity,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TPCN1 itself. We selected most functions TPCN1 had, and list some proteins which have the same functions with TPCN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NAADP-sensitive calcium-release channel activity | MCOLN1,TPCN2 |
| identical protein binding | CHAF1A,LTBR,APP,RIPK3,ATL3,KCTD17,RAD52,ATXN10,THBS1,MAP3K13 |
| calcium channel activity | TRPV5,CACNA1BA,PDE2A,RYR1B,TRPM2,TRPC2,PKD2L1,CACNA1SA,CACNG7A,GPM6A |
| ion channel activity | ITPR3,P2RX3B,CHRNA2A,DDX1,FXYD7,GRIN2A,KCNV2B,KCNC3B,TRPM5,GRIA2A |
| voltage-gated ion channel activity | CLIC4,CACNG2A,KCNJ2A,KCNK10,CACNA1SA,SCN4AA,KCNH5,CLIC5A,TPC3,KCNG4A |
Interacting Protein
TPCN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPCN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TPCN1.
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References
- Lin, JH; Zhang, HH; et al. Simultaneous determination of carcinoembryonic antigen and alpha-fetoprotein using an ITO immunoelectrode modified with gold nanoparticles and mesoporous silica. MICROCHIMICA ACTA 182:719-726(2015).
- Lin, JH; Zhang, HH; et al. A Label-free Immunosensor based on Ionic Liquids Modified Mesoporous Silica for Simultaneous Determination of Two Tumor Markers. ACTA CHIMICA SINICA 72:241-245(2014).
