TP53AIP1
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Official Full Name
tumor protein p53 regulated apoptosis inducing protein 1 -
Overview
This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. -
Synonyms
TP53AIP1;tumor protein p53 regulated apoptosis inducing protein 1;p53-regulated apoptosis-inducing protein 1;p53AIP1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TP53AIP1-3361H | Recombinant Human TP53AIP1, GST-tagged | E.coli | Human | GST | 1-108aa | |
| TP53AIP1-2278H | Recombinant Human TP53AIP1 protein, His-tagged | E.coli | Human | His | 1-124 a.a. |
|
Involved Pathway
TP53AIP1 involved in several pathways and played different roles in them. We selected most pathways TP53AIP1 participated on our site, such as p signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TP53AIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| p signaling pathway | CCNE2,SERPINE1,PPM1DB,IGF1,PTENB,SERPINB5,RFWD2,TNFRSF10B,CASP9,BIDA |
Protein Function
TP53AIP1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by TP53AIP1 itself. We selected most functions TP53AIP1 had, and list some proteins which have the same functions with TP53AIP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | HSCB,FHAD1,UBALD1B,CCDC149B,ACSM2B,BEST3,PRPF38A,TMEM120A,SIRP-BETA,TSPYL5 |
Interacting Protein
TP53AIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TP53AIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TP53AIP1.
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References
- De la Rosa, AJ; Gomez, MA; et al. CD95 Signaling in Cancer Treatment. CURRENT PHARMACEUTICAL DESIGN 20:2809-2818(2014).
- Allen, JE; Krigsfeld, G; et al. Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects. SCIENCE TRANSLATIONAL MEDICINE 5:-(2013).
